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Fig. 3 | Respiratory Research

Fig. 3

From: From bench to bedside: in vitro and in vivo evaluation of a neonate-focused nebulized surfactant delivery strategy

Fig. 3

Box-plots showing (a) the oxygenation index (OI) and (b) ventilation efficacy index (VEI) at baseline (from all animals), after inducing a respiratory distress (Post BALs, from all animals) and 180 min after treatment with just nasal continuous positive pressure ventilation (nCPAP), with different doses of nebulized surfactant (Neb-SURF100, Neb-SURF200, Neb-SURF400, Neb-SURF600) or with intratracheal surfactant (Inst-SURF). The boxes encompass the 25–75 percentiles. The horizontal line within the boxes represents the median. The whiskers indicate the maximum and minimum values observed for each group. * P vs. nCPA P < 0.01; # P vs. Inst-SURF < 0.05

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