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Table 2 Lung cancer incidence per 10,000 person-years by age in patients with connective tissue disease-associated interstitial lung disease (CTD-ILD) and interstitial lung disease (ILD)-only

From: Lung Cancer development and mortality in interstitial lung disease with and without connective tissue diseases: a five-year Nationwide population-based study

 

CTD-ILD

ILD-only

  

Age (years)

Population (n)

Lung cancer cases (n)

Person-years of follow-up

Incidence

Population (n)

Lung cancer cases (n)

Person-years of follow-up

Incidence

RR

95% CI

P value

E value

40–49

472

19

2054.3

92.5

1667

28

6924.3

40.4

2.28

1.20–4.24

0.01

3.60 (1.00-NA)

50–59

685

40

2873.7

139.2

2679

95

11,109.3

85.5

1.62

1.09–2.38

0.01

2.87 (1.43-NA)

60–69

753

59

2988.0

197.5

3535

220

14,041.9

156.7

1.26

0.92–1.68

0.13

 

70–79

493

41

1768.7

231.8

3446

258

12,371.2

208.5

1.11

0.77–1.55

0.57

 

>  80

88

6

271.4

221.1

1460

96

4232.2

226.8

0.97

0.34–2.20

1.00

 

Total

2491

165

9956.1

165.7

12,787

697

48,679.0

143.2

1.15

0.97–1.37

0.10

 
  1. RR, rate ratio; CI, confidence interval; NA, not available; E value was calculated by VanderWeele and Ding method [29]
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Respiratory Research

ISSN: 1465-993X

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