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Table 2 Bronchoscopic intervention*

From: Bleeding risk of transbronchial cryobiopsy compared to transbronchial forceps biopsy in interstitial lung disease – a prospective, randomized, multicentre cross-over trial

Variable

N = 359 (100%)

Number of biopsies

 Cryobiopsy

  Total number of cryobiopsies

1160

  Cryobiopsies per patient

3,2 ± 1,2

 Forceps biopsy

  Total number of forceps biopsies

1302

  Forceps biopsies per patient

3,6 ± 1,2

Sedation – no. (%)

 General anaesthesia

169 (47.1)

 Deep sedation

185 (51.5)

Deep sedation

 Midazolam

  Number of patients

115

  Dose – mg

3.57 (±1.66)

 Propofol

  Number of patients

168

  Dose – mg

315.2 (±166.9)

Intubation technique – no. (%)

 

 Rigid bronchoscope

169 (47.6)

 Endotracheal tube intubation

182 (51.3)

 No intubation

4 (1.1)

Probe size

 Cryobiopsy – no. (%)

  Small

   1.9 mm

212 (59.1)

  Large

   2.4 mm

145 (40.4)

 Forceps – no. (%)

  Small

   total

169 (47.1)

   1.8 mm

145 (40.4)

   2.0 mm

24 (6.7)

  Large

   total

186 (51.8)

   2.2 mm

161 (44.8)

   2.6 mm

25 (7.0)

 

Biopsy technique

TBCB

TBFB

Localization of biopsy - no. (%)

 Biopsy in different lobes

151 (42.1)

189 (52.6)

 Biopsy in just one lobe

205 (57.1)

166 (46.2)

 Right upper lobe and middle lobe

284 (24.5)

357 (27.4)

 Left upper lobe

134 (11.6)

159 (12.2)

 Right lower lobe

528 (45.5)

543 (41.7)

 Left lower lobe

214 (18.4)

243 (18.7)

  1. *Plus-minus values are means ± Standard deviation (SD). Data were unknown as follows: for sedation in 5 patients (1.4%), midazolam application in 15 patients (4.2%), propofol application in 30 patients (8.4%), intubation technique in 4 patients (1.1%), probe size of cryobiopsy in 1 patient (0.3%), and probe size of forceps in 4 patients (1.1%) and localization of cryobiopsy/ forceps biopsy in 4/ 4 patients (1.1/ 1.1%). TBCB – transbronchial lung cryobiopsy; TBFB – transbronchial lung forceps biopsy