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Fig. 5 | Respiratory Research

Fig. 5

From: Transection of the cervical sympathetic trunk inhibits the progression of pulmonary arterial hypertension via ERK-1/2 Signalling

Fig. 5

TCST attenuated MCT-induced proliferation and increased cyclin protein expression in vivo. a TCST decreased the upregulated expression of PCNA induced by MCT. b, c The upregulated expression of cyclin A2 and cyclin D1 induced by MCT was inhibited by TCST. d ERK activation in the pulmonary vasculature in the different groups. **P < 0.01 vs. control group; #P < 0.01 vs. MCT group; &P < 0.01 vs. MCT + sham group. e NE led to a significant increase in cell viability at a concentration of 1 μM. **P < 0.01 vs. control group; (f) Different concentrations of Pra inhibited the NE-induced increase in cell viability. *P < 0.05 vs. NE group

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Respiratory Research

ISSN: 1465-993X

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