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Fig. 2 | Respiratory Research

Fig. 2

From: Airway host-microbiome interactions in chronic obstructive pulmonary disease

Fig. 2

Sputum microbiome profiles in healthy subjects and COPD patients. a Shannon diversity and relative abundance of major bacterial taxa in healthy controls and stable COPD patients, and in healthy and COPD subgroups in relation to smoking status. b Shannon diversity and relative abundances of major bacterial taxa in COPD patients at different visits. The number of samples in each group is indicated in the parenthesis. Significantly differentially represented bacterial taxa were identified using edgeR [27]. For visit, statistical analysis was performed on each adjacent two time points. E0: COPD exacerbations, E2: 2 week post-exacerbations, E6: 6 week post-exacerbations, 6 Months: 6 months from first stable visit, HNS: healthy non-smokers, HS: healthy smokers, CS: COPD current smokers, ES: COPD ex-smokers. *** FDR P < 0.001, ** FDR P < 0.01, * FDR P < 0.05

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