From: SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model
Gene Identification | Fold-Change vs. Normoxia | ||||
---|---|---|---|---|---|
Symbol | Gene Name | CH-PH | P-value | SU/CH-PH | P-value |
Angpt2 | Angiopoietin 2 | 2.75 | 0.003788 | 2.61 | 0.005498 |
Ccl2 | Chemokine (C-C) motif ligand 2 | 7.76 | 0.019500 | 8.39 | 0.024364 |
Col18a1 | Collagen, type XVIII, alpha 1 | 3.70 | 0.000009 | 3.60 | 0.010498 |
Cxcl2 | Chemokine (C-X-C) motif ligand 2 | 2.70 | 0.008983 | 3.24 | 0.005886 |
Eng | Endoglin | 3.08 | 0.002967 | 2.02 | 0.034330 |
Fn1 | Fibronectin 1 | 4.05 | 0.004777 | 3.19 | 0.031768 |
Hgf | Hepatocyte growth factor | 2.85 | 0.000241 | 2.27 | 0.001051 |
Kdr | Kinase insert domain protein receptor | 3.15 | 0.031063 | 2.08 | 0.049350 |
Mmp14 | Matrix metallopeptidase 14 | 3.58 | 0.005553 | 2.77 | 0.002366 |
Nrp2 | Neuropilin 2 | 3.50 | 0.004670 | 3.33 | 0.004227 |
Pecam1 | Platelet/endothelial cell adhesion molecule-1 | 3.65 | 0.009939 | 2.33 | 0.049902 |
Plau | Plasminogen activator, urokinase | 4.27 | 0.013232 | 3.07 | 0.014172 |
Ptk2 | PTK2 protein tyrosine kinase 2 | 2.76 | 0.033783 | 2.03 | 0.012938 |
Tgfb1 | Transforming growth factor, beta 1 | 2.77 | 0.011717 | 2.51 | 0.010149 |