Fig. 5
From: SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model
Effects of SU5416 on the relationship between RV microvascular remodeling and RV cardiomyocyte size. The relationship between total RV capillary length (a), surface area (b), and lumen volume (c) and RV cardiomyocyte (CM) volume is shown by linear regression. The slope of each line represents an estimate of relative growth, with a slope of 1.0 demonstrating isometry. Normoxic (open), CH-PH (red), and SU5416/CH-PH (blue) treated animals fall on the same curve. When compared against one another, the slopes were not significantly different (P = 0.60), suggesting similar rates of relative growth among all microvascular parameters (when compared with CM volume). Dotted lines represent 95% confidence interval of regression line