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Fig. 3 | Respiratory Research

Fig. 3

From: SU5416 does not attenuate early RV angiogenesis in the murine chronic hypoxia PH model

Fig. 3

Effects of SU5416 on RV angiogenesis in the CH-PH model. After 1 week of exposure to CH-PH, SU5416 had no effect on observed increases in total RV capillary length (a; Lcap), surface area (b; Scap), or volume (c; Vcap), as estimated by unbiased stereological methods. Similarly, there was no effect of SU5416 on CH-PH induced increases in RV myocyte volume (d; Vmyo) or RV volume (e; VRV), and the estimated radius of tissue served/vessel did not change in either group (f). P-values are for one-way ANOVA. * denotes P < 0.05, ** denotes P < 0.01, and *** denotes P < 0.001 in comparison to normoxic controls (Norm). Data from all animals are shown; n = 11 animals/group

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