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Table 4 Pulmonary function at baseline and post AITC cough challenge of subjects

From: Heterogeneity of cough hypersensitivity mediated by TRPV1 and TRPA1 in patients with chronic refractory cough

 

Healthy subjects

Patients with CRC

Baseline

Post challenge

P

Baseline

Post challenge

P

FEV1 (L)

3.5 ± 0.4

3.5 ± 0.4

0.733

3.6 ± 0.8

3.5 ± 0.8

0.168

FEV1% pred

102.4 ± 12.2

102.3 ± 12.7

0.808

96.3 ± 7.8

95.6 ± 8.1

0.133

FVC (L)

4.0 ± 0.6

4.0 ± 0.6

0.421

4.2 ± 0.9

4.2 ± 0.9

0.226

FVC % pred

100.4 ± 13.1

100.2 ± 13.0

0.590

95.8 ± 9.1

96.9 ± 10.2

0.129

FEV1 / FVC

86.5 ± 4.9

86.5 ± 5.0

0.991

85.4 ± 5.8

85.3 ± 6.4

0.879

MMEF (L)

4.2 ± 0.7

4.2 ± 0.9

0.116

3.9 ± 1.5

3.9 ± 1.4

0.746

MMEF % pred

100.5 ± 20.1

100.3 ± 20.2

0.205

83.6 ± 19.8

83.5 ± 17.1

0.915

  1. Data are expressed as mean ± SD. CRC chronic refractory cough, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, MMEF maximum mid-expiratory flow