From: Risk factors for diagnostic delay in idiopathic pulmonary fibrosis
Patient delay | Healthcare delay | Total delay | |||||||
---|---|---|---|---|---|---|---|---|---|
IRR | 95% CI | p-value | IRR | 95% CI | p-value | IRR | 95% CI | p-value | |
Patient characteristics | |||||||||
Age | 0.97 | 0.92–1.02 | 0.24 | 1.03 | 1.01–1.06 | 0.004* | 1.01 | 0.98–1.03 | 0.59 |
Male sex | 3.84 | 1.17–11.36 | 0.006* | 1.01 | 0.68–1.49 | 0.95 | 0.99 | 0.66–1.48 | 0.97 |
Ever smokers | 1.34 | 0.48–3.35 | 0.51 | 0.78 | 0.54–1.11 | 0.18 | 0.79 | 0.54–1.14 | 0.19 |
Higher education | 2.16 | 0.91–5.18 | 0.06 | 1.28 | 0.91–1.81 | 0.14 | 1.15 | 0.83–1.60 | 0.39 |
Previous use of inhalation therapy | 4.68 | 1.77–13.37 | 0.0004* | 1.98 | 1.38–2.90 | < 0.0001* | 1.99 | 1.40–2.88 | < 0.0001* |
Clinical findings at diagnosis | |||||||||
DLCO (%) | 1.05 | 1.02–1.08 | 0.005* | 1.02 | 1.01–1.03 | 0.006* | 1.02 | 1.00–1.03 | 0.02* |
FVC (%) | 1.02 | 0.99–1.05 | 0.06 | 1.00 | 0.99–1.01 | 0.96 | 1.00 | 0.99–1.01 | 0.67 |
Airway obstruction | 1.10 | 0.23–3.86 | 0.89 | 1.57 | 0.86–2.66 | 0.11 | 1.61 | 0.94–2.61 | 0.07 |
SGRQ total score | 1.03 | 1.01–1.07 | 0.004* | 1.01 | 1.00–1.03 | 0.003* | 1.02 | 1.01–1.03 | 0.001* |
UIP pattern on HRCT | 0.84 | 0.30–2.11 | 0.71 | 1.32 | 0.89–1.95 | 0.16 | 1.47 | 1.01–2.11 | 0.04* |