Table 1 Baseline characteristics of participants with a delay above or below 2 years
From: Risk factors for diagnostic delay in idiopathic pulmonary fibrosis
All patients (n = 204) | Total delay > 2 years (n = 98) | Total delay < 2 years (n = 92) | P-value | |
|---|---|---|---|---|
Age (years), mean (SD) | 73.7 (7.8) | 73.2 (8.0) | 73.5 (7.6) | 0.79 |
Sex | 0.79 | |||
Male, n (%) | 158 (77.5%) | 74 (75.5%) | 71 (77.2%) | |
Female, n (%) | 46 (22.5%) | 24 (24.5%) | 21 (22.8%) | |
Smoking status | 0.28 | |||
Never, n (%) | 52 (25.6%) | 31 (31.6%) | 20 (21.7%) | |
Active, n (%) | 14 (6.9%) | 6 (6.1%) | 8 (8.7%) | |
Former, n (%) | 137 (67.5%) | 61 (62.2%) | 64 (69.6%) | |
Pack-years, median (IQR) | 25.0 (11.8–40.0) | 26.5 (10.9–40.0) | 20.0 (10.8–41.7) | 0.68 |
BMI (kg/m2), mean (SD) | 27.4 (4.6) | 28.0 (4.4) | 26.8 (4.9) | 0.08 |
Education | 0.67 | |||
No higher education, n (%) | 101 (54.9%) | 52 (56.5%) | 47 (53.4%) | |
Higher education, n (%) | 83 (45.1%) | 40 (43.5%) | 41 (46.6%) | |
Previous use of inhalation therapy | < 0.01 | |||
No, n (%) | 143 (70.1%) | 59 (60.2%) | 76 (82.6%) | |
Yes, n (%) | 61 (29.9%) | 39 (39.8%) | 16 (17.4%) | |
Airway obstruction at baseline | 0.75 | |||
No, n (%) | 179 (88.2%) | 87 (88.8%) | 83 (90.2%) | |
Yes, n (%) | 24 (11.8%) | 11 (11.2%) | 9 (9.8%) | |
FVC (l), mean (SD) | 3.0 (0.8) | 3.0 (0.8) | 3.1 (0.9) | 0.60 |
FVC (% pred.), mean (SD) | 88.9 (19.0) | 87.9 (16.8) | 91.1 (21.6) | 0.25 |
DLCO (% pred.), mean (SD) | 52.6 (13.6) | 52.6 (13.6) | 53.0 (13.5) | 0.84 |
6MWT-distance (m), mean (SD) | 441.7 (106.5) | 444.8 (108.1) | 448.3 (93.2) | 0.82 |
SaO2 at rest (%), mean (SD) | 96.2 (1.9) | 96.3 (1.8) | 96.2 (1.9) | 0.82 |
SaO2 after 6MWT (%), mean (SD) | 88.2 (7.7) | 88.2 (7.0) | 88.3 (8.2) | 0.92 |
SGRQ total score, mean (SD) | 39.1 (19.6) | 41.4 (17.8) | 37.2 (21.4) | 0.20 |