BPD n = 26 | Preterm n = 23 | Asthma n = 23 | Healthy controls n = 24 | |
---|---|---|---|---|
Male/Female | 11/15 | 10/13 | 10/13 | 12/12 |
Gestational age at birth, weeks | 26### (24–31) | 29.5 (26–32) | 40 (38–42) | 40 (37–43) |
Birth weight, g | 960### (583–1510) | 1470 (659–2200) | 3505 (2660–4840) | 3458 (2670–4550) |
Small for gestational age | 8 (31) | 7 (30) | 0 | 0 |
Maternal smoking during pregnancy | 7 (27) | 3 (13) | 2 (9) | 5 (21) |
Prenatal corticosteroid therapy | 11 (42) | 10 (43) | N/A | N/A |
Caesarean section | 13 (50) | 18 (78) | 1 (4) | 1 (4) |
Multiple birth | 8 (31) | 12 (52) | 0 | 0 |
Apgar score at 1 min | 5 (1–9)*** | 8 (4–10) | 9 (5–10) | 9 (5–9) |
Apgar score at 5 min | 7 (3–10)*** | 9 (3–10)** | 10 (7–10) | 10 (8–10) |
Instillation of surfactant | 8 (31) | 2 (4) | N/A | N/A |
Ventilator therapy, days | 4 (0–38) | 0 (0–8) | N/A | N/A |
CPAP, days | 41 (3–70) | 3 (0–19) | N/A | N/A |
Supplemental O2, days | 67 (28–180) | 3 (1–26) | N/A | N/A |
Septicemia | 16 (62)## | 6 (26) | N/A | N/A |
PDA, treated | 8 (31)## | 0 | N/A | N/A |
ROP grade 3–4 | 7 (27) | 3 (13) | N/A | N/A |