Skip to main content

Table 1 Baseline characteristicsa

From: Reliability, validity and responsiveness of E-RS:COPD in patients with spirometric asthma-COPD overlap

  Overall population (N = 338)
Age (years), mean (SD) 57.5 (10.6)
 ≥40 years, n (%) 321 (95)
 < 40 years, n (%) 17 (5)
Male, n (%) 178 (53)
Ethnicity n, (%)
 Hispanic/Latino 13 (4)
 Not Hispanic/Latino 325 (96)
Body mass index (kg/m2), mean (SD) 27.9 (5.0)
Primary diagnosis, n (%)
 Asthma 183 (54)
 COPD 155 (46)
Smoking status, n (%)
 Never 125 (37)b
 Former 129 (38)
 Current 84 (25)
Pack yearsc, mean (SD) 24.4 (21.8)
Pre-bronchodilator FEV1 (L), mean (SD) 1.57 (0.5)
Pre-bronchodilator FEV1 (% predicted), mean (SD) 51.0 (8.2)
Post-bronchodilator FEV1 (% predicted), mean (SD) 64.8 (7.7)
Pre-bronchodilator FEV1/FVC (%), mean (SD) 50.5 (8.1)
Post-bronchodilator FEV1/FVC, (%), mean (SD) 55.5 (7.8)
FEV1 reversibility (mL), mean (Sd) 423.0 (184.0)
E-RS Total score (range: 0–40), mean (SD) 10.7 (6.1)
SGRQ Total score (range: 0–100), mean (SD) 44.0 (15.3)
 SGRQ Activity score (range: 0–100), mean (SD) 53.7 (18.5)
 SGRQ Impacts score (range: 0–100), mean (SD) 33.7 (17.0)
 SGRQ Symptoms score (range: 0–100), mean (SD) 60.0 (19.4)
mMRC dyspnea scale score (range: 0–4), mean (SD) 1.8 (0.7)
 0–1, n (%) 114 (34)
  ≥ 2, n (%) 224 (66)
Blood eosinophils, n (%)
  < 0.15 GI/L 135 (42)
  ≥ 0.15 GI/L 183 (58)
Wheeze score (range: 0–4), mean (SD) 0.9 (0.8)
  1. aData adapted from Lee et al., 2017, Respir Med, published by Elsevier. This is an open access article under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives 4.0 International License (https://doi.org/10.1016/j.rmed.2017.08.013) [24]; bOf whom, 102 and 23 patients had asthma or COPD as a primary diagnosis, respectively; cn = 213. dTT: FEV1 reversibility was < 400 mL for 185 patients (55%) and ≥ 400 mL for 153 patients (45%)
  2. COPD chronic obstructive pulmonary disease, E-RS Evaluating Respiratory Symptoms in COPD, FEV1 forced expiratory volume in 1 s, FVC forced vital capacity, mMRC Modified Medical Research Council, SD standard deviation, SGRQ St George’s Respiratory Questionnaire