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Table 3 ROC Analyses of s3/s2 and the combined capnovolumetric score for different stages of airway obstruction

From: Diagnostic accuracy of capnovolumetry for the identification of airway obstruction – results of a diagnostic study in ambulatory care

Airway obstruction (AO)

s3/s2

Combined capnovolumetric score

cut-off

sensitivity (%)

specificity (%)

AUC ± SEM (95% CI)

cut-off

sensitivity (%)

specificity (%)

AUC ± SEM (95% CI)

AO in spirometry / bodyplethysmography*

0.10

47.7 (42.7;52.8)

79.0 (76.3; 81.6)

0.678 ± 0.017 (0.645; 0.710)

0.26

69.8 (65.1; 74.7)

71.7 (67.7; 73.7)

0.772 ± 0.015 (0.743; 0.801)

FEV1 ≤ 80

0.10

46.2 (41.7; 50.8)

81.0 (78.2; 83.6)

0.699 ± 0.015 (0.669; 0.729)

0.26

64.8 (60.5; 69.3)

72.7 (69.0; 75.1)

0.743 ± 0.015 (0.713; 0.772)

FEV1 ≤ 50

0.10

75.9 (67.1; 83.0)

75.8 (73.3; 78.1)

0.851 ± 0.016 (0.820; 0.883)

0.26

88.9 (80.5; 92.8)

62.6 (60.6; 66.1)

0.854 ± 0.019 (0.818; 0.890)

FEV1 ≤ 30

0.10

86.7 (70.3; 94.7)

72.8 (70.3; 75.2)

0.887 ± 0.025 (0.838; 0.935)

0.26

93.3 (78.7; 98.2)

60.3 (57.6; 63.0)

0.860 ± 0.025 (0.810; 0.909)

  1. The table shows the results of ROC analyses with s3/s2 and the combined capnovolumetric score for the recognition of different degrees of airway obstructions defined by restrictions in FEV1. FEV1, forced expiratory volume in one second; AO Airway obstruction, AUC area under the curve, SEM standard error mean, 95% CI 95% confidence interval. (* z-Score FEV1/FVC < −1.645 and / or sRAW > 1.2 kPa*s)