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Table 3 ROC Analyses of s3/s2 and the combined capnovolumetric score for different stages of airway obstruction

From: Diagnostic accuracy of capnovolumetry for the identification of airway obstruction – results of a diagnostic study in ambulatory care

Airway obstruction (AO) s3/s2 Combined capnovolumetric score
cut-off sensitivity (%) specificity (%) AUC ± SEM (95% CI) cut-off sensitivity (%) specificity (%) AUC ± SEM (95% CI)
AO in spirometry / bodyplethysmography* 0.10 47.7 (42.7;52.8) 79.0 (76.3; 81.6) 0.678 ± 0.017 (0.645; 0.710) 0.26 69.8 (65.1; 74.7) 71.7 (67.7; 73.7) 0.772 ± 0.015 (0.743; 0.801)
FEV1 ≤ 80 0.10 46.2 (41.7; 50.8) 81.0 (78.2; 83.6) 0.699 ± 0.015 (0.669; 0.729) 0.26 64.8 (60.5; 69.3) 72.7 (69.0; 75.1) 0.743 ± 0.015 (0.713; 0.772)
FEV1 ≤ 50 0.10 75.9 (67.1; 83.0) 75.8 (73.3; 78.1) 0.851 ± 0.016 (0.820; 0.883) 0.26 88.9 (80.5; 92.8) 62.6 (60.6; 66.1) 0.854 ± 0.019 (0.818; 0.890)
FEV1 ≤ 30 0.10 86.7 (70.3; 94.7) 72.8 (70.3; 75.2) 0.887 ± 0.025 (0.838; 0.935) 0.26 93.3 (78.7; 98.2) 60.3 (57.6; 63.0) 0.860 ± 0.025 (0.810; 0.909)
  1. The table shows the results of ROC analyses with s3/s2 and the combined capnovolumetric score for the recognition of different degrees of airway obstructions defined by restrictions in FEV1. FEV1, forced expiratory volume in one second; AO Airway obstruction, AUC area under the curve, SEM standard error mean, 95% CI 95% confidence interval. (* z-Score FEV1/FVC < −1.645 and / or sRAW > 1.2 kPa*s)