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Fig. 4 | Respiratory Research

Fig. 4

From: Tobacco exposure inhibits SPLUNC1-dependent antimicrobial activity

Fig. 4

Tobacco smoke exposure reduces SPLUNC1 bacteriostatic activity. a, c 10 μM of SPLUNC1 or Kentucky cigarette-exposed SPLUNC1 dissolved in Ringer’s solution were co-incubated with 106 of H. influenzae or P. aeruginosa for 24 h (all n = 3 per group). b, d H. influenzae or P. aeruginosa were co-incubated with 10 μM of SPLUNC1 or tobacco-exposed SPLUNC1 for 24 h; Camel, Marlboro, Djarum, Cheyenne, Swisher Sweets, Swisher Sweets Strawberry, and Captain Black (all n = 3 per group). Statistically significant differences were measured using Kruskal-Wallis test. *p < 0.05, **p < 0.01, ***p < 0.001 different to control

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