Fig. 4From: Single-photon emission computed tomography/computed tomography imaging of RAGE in smoking-induced lung injuryIncreased HMGB1 immunofluorescence in alveolar macrophages after 4-weeks of smoke exposure. In 4-week smoke exposed rabbit lung, HMGB1 (red colour) localizes to the macrophage cytoplasm. Nuclei are stained blue. Representative images are provided, with white arrows denoting areas of cells with increased HMGB1 staining. Images were taken at 20X magnificationBack to article page