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Fig. 7 | Respiratory Research

Fig. 7

From: Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia

Fig. 7

Modulation of superoxide dismutase (Sod) 2 expression through hyperoxia and caffeine. Quantitation of lung homogenates by a) ELISA and b) qPCR of for 3 days’ postnatal oxygen exposure (P3) and recovery (P3_P15), and 5 days’ postnatal oxygen exposure (P5) and recovery (P5_P15), respectively. Data are expressed relative to the normoxia-exposed control group (100%) and the 100% values for ELISA quantitation are 97.7 pg/mg, 70.4 pg/mg, 78.3 pg/mg, and 72.9 pg/mg protein for P3 and P3_P15 or P5 and P5_P15 groups, respectively. Error bars represent SEM, n = 5 (ELISA) or n = 7–8 (pPCR)/group. *p < 0.05, **p < 0.01, and ***p < 0.001 versus control (NO); #p < 0.05, ##p < 0.01, and ###p < 0.001 versus hyperoxia group (HY) with Mann Whitney test

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