Fig. 5
From: Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia
Acute hyperoxia resulted in an adequate oxidative stress response and caffeine reduced the response. Quantitation of lung homogenates by qPCR of a) Nrf2, and b) Keap1 for 3 days’ postnatal oxygen exposure (P3) and recovery (P3_P15), and 5 days’ postnatal oxygen exposure (P5) and recovery (P5_P15), respectively. Data are expressed relative to the normoxia-exposed control group (100%). Error bars represent SEM, n = 7–8/group. *p < 0.05, **p < 0.01, and ***p < 0.001 versus control (NO); #p < 0.05, ##p < 0.01, and ###p < 0.001 versus hyperoxia group (HY) with Mann Whitney test