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Fig. 1 | Respiratory Research

Fig. 1

From: Antioxidative effects of caffeine in a hyperoxia-based rat model of bronchopulmonary dysplasia

Fig. 1

Time course of hyperoxic exposure and recovery of rat pups. The pups were divided into four groups with exposure to room air or hyperoxia occurring for either a) 3 postnatal days (P0-P3) or b) 5 postnatal days (P0-P5) with normoxia (NO) and vehicle application (PBS), normoxia with caffeine application (NOC), hyperoxia (HY) and vehicle application, and hyperoxia with caffeine (HYC). Rat pups received caffeine or vehicle injection intraperitoneally as a fixed portion of body weight (100 μl/10 g) every 48 h beginning on the day of birth (P0, red arrow). The experimental endpoints (black arrow) are directly after the oxygen exposure (P3 or P5) and after recovery in room air at P15 (P3_P15 or P5_P15)

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