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Fig. 3 | Respiratory Research

Fig. 3

From: Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia

Fig. 3

Pulmonary expression of Arg1 in wild-type and NOS2−/− mice. The level of Arg1 protein was low in the lungs of saline-treated wild-type mice (N = 6) and was markedly increased in the lungs of wild-type mice treated with LPS (N = 6). Arg1 protein level were low in NOS2−/− mice challenged with saline (control, N = 4) or endotoxin (N = 5). Lungs were harvested 22 h after challenge with either saline (control) or lipopolysaccharide (LPS). Data are presented as mean ± SD; * P < 0.05 vs. saline-challenged wild-type mice, # P < 0.05 vs. saline-challenged NOS2−/− mice, and § P < 0.05 vs. endotoxin-challenged NOS2−/− mice

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