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Fig. 2 | Respiratory Research

Fig. 2

From: Arginase impairs hypoxic pulmonary vasoconstriction in murine endotoxemia

Fig. 2

Pulmonary mRNA expression of Arg1 and Arg2 in wild-type mice and NOS2−/− mice. Endotoxin increased the pulmonary Arg1 mRNA expression in wild-type mice but not in NOS2−/− mice (Panel a). The pulmonary Arg2 mRNA expression was similar in wild-type mice and NOS2−/− mice after LPS challenge (Panel b). Tissue samples were taken 22 h after challenge with either saline (control) or LPS. N = 6 per group; data are presented as mean ± SD; * P < 0.05 vs. saline-challenged wild-type mice, # P < 0.05 vs. saline-challenged NOS2−/− mice, and § P < 0.05 vs. endotoxin-challenged NOS2−/− mice

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