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Fig. 4 | Respiratory Research

Fig. 4

From: Bradykinin sensitizes the cough reflex via a B2 receptor dependent activation of TRPV1 and TRPA1 channels through metabolites of cyclooxygenase and 12-lipoxygenase

Fig. 4

Effect of i.c.v. administered TRPA1 channel antagonist, HC-030031 (HC) 60 nmole ml− 1 (n = 8) and 150 nmole ml− 1 (n = 8)versus vehicle (n = 13), on BK-enhanced citric acid-induced cough (a) changes in Penh (b) and Penh AUC (c). Values represent means + sem. * p < 0.05, significant difference compared to vehicle/BK treated animals

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Respiratory Research

ISSN: 1465-993X

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