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Table 3 Number of subjects having an event (%) and hazard ratio (95% confidence interval) of time to all-cause death, moderate/severe COPD exacerbation, severe COPD exacerbation, and cardiovascular composite event among participants with thrombocytopenia (platelet count < 150 × 109 /L) and high platelet count (≥ 300 × 109 /L) compared with normal platelet count (≥150 to < 300 × 109 /L)

From: Association of platelet count with all-cause mortality and risk of cardiovascular and respiratory morbidity in stable COPD

Event

Platelet count < 150 × 109 /L

N = 167

Platelet count ≥150 × 109 /L to < 300 × 109 /L

N = 1424

Platelet count ≥300 × 109 /L

N = 206

All-cause death

14 (8%)

73 (5%)

19 (9%)

1.46 (0.81, 2.64)

-REF-

1.66 (0.96, 2.86)

Cardiovascular composite

6 (4%)

68 (5%)

12 (6%)

0.55 (0.23, 1.30)

-REF-

1.55 (0.82, 2.94)

Moderate/Severe COPD exacerbation

64 (38%)

508 (36%)

79 (38%)

1.15 (0.88, 1.50)

-REF-

1.05 (0.82, 1.34)

Severe COPD exacerbation

15 (9%)

123 (9%)

21 (10%)

0.95 (0.55, 1.66)

-REF-

1.21 (0.75, 1.96)