Table 2 Baseline characteristics of patients in tiotropium and non-tiotropium groups after propensity score matching
Tiotropium group | Non-tiotropium group | P value | |
|---|---|---|---|
Patients number | 105 | 105 | |
Age (years) | 63.9 ± 9.7 | 64.4 ± 9.6 | 0.715 |
Male sex | 79 (75.2) | 76 (72.4) | 0.638 |
Body mass index, kg/m2 | 21.2 ± 3.5 | 21.2 ± 3.6 | 0.929 |
Ever-smokers | 67 (63.8) | 71 (67.6) | 0.561 |
mMRC dyspnea scale | 0.980 | ||
- 0 | 16 (15.2) | 17 (16.2) | |
- 1 | 41 (39.0) | 40 (38.1) | |
- 2 | 29 (27.6) | 30 (28.6) | |
- 3 | 12 (11.4) | 13 (12.4) | |
- 4 | 7 (6.7) | 5 (4.8) | |
Charlson Comorbidity Index | 2.2 ± 1.8 | 2.3 ± 1.8 | 0.566 |
Concomitant asthma | 14 (13.3) | 15 (14.3) | 0.842 |
Concomitant COPD | 63 (60.0) | 61 (58.1) | 0.779 |
ICS/LABA usage | 18 (17.1) | 18 (17.1) | > 0.999 |
Pulmonary function tests | |||
FEV1, % predicted | 45.0 ± 15.0 | 45.3 ± 16.5 | 0.903 |
FVC, % predicted | 62.0 ± 17.6 | 62.0 ± 18.8 | 0.976 |
FEV1/FVC ratio, % | 56.0 ± 17.1 | 55.6 ± 16.4 | 0.863 |
DLco, % predicted | 52.5 ± 20.9 | 54.1 ± 14.2 | 0.688 |
X-ray severity score (0 to 6) | 3.4 ± 1.2 | 3.3 ± 1.3 | 0.786 |
Long-term oxygen therapy | 10 (9.5) | 13 (12.4) | 0.507 |