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Table 2 Change from baseline parameters after the 12-month follow-up for the N-acetylcysteine and control groups

From: Effect of N-acetylcysteine on exacerbations of bronchiectasis (BENE): a randomized controlled trial

  Control group N-acetylcysteine group P value
CAT score −1.44 ± 6.19 −3.79 ± 5.40 0.011
24-h sputum volume, mL −6.46 ± 22.73 −18.28 ± 25.69 0.002
ESR −0.36 ± 8.74 −4.21 ± 10.57 0.115
CRP −1.68 ± 9.62 −2.83 ± 6.68 0.089
Pseudomonas aeruginosa positive, n (%) −5 (25.0) −8 (29.6) 0.726
Pulmonary function
 FVC, L 0.03 ± 0.22 0.01 ± 0.46 0.991
 FEV1, L 0.03 ± 0.16 −0.10 ± 0.37 0.210
 Predicted FEV1, % 0.13 ± 7.78 1.16 ± 16.50 0.445
 FEV1/FVC, % −0.29 ± 4.29 0.53 ± 7.45 0.394
 Inspiratory capacity, L 0.01 ± 0.22 0.06 ± 0.24 0.098
  1. Data are n (%) or mean ± SD. Abbreviations: CAT chronic obstructive pulmonary disease assessment test, FVC forced vital capacity, FEV1 forced expiratory volume in 1 s, ESR erythrocyte sedimentation rate, CRP C-reactive protein