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Table 1 Comparison of clinical characteristics between patients with ACO versus patients with COPD alone

From: Differences in the risk of mood disorders in patients with asthma-COPD overlap and in patients with COPD alone: a nationwide population-based retrospective cohort study in Korea

Category

No. of patients (%)

P value

Standardized differencea

ACO (n = 7822)

COPD alone (n = 7822)

Age group (years)

 40–64

3700(47.3)

3718(47.53)

0.7732

0.00461

  ≥ 65

4122(52.7)

4104(52.47)

Sex

 Male

4170(53.31)

4176(53.39)

0.9234

0.00154

 Female

3652(46.69)

3646(46.61)

Charlson comorbidity index

 0

1436(18.36)

1537(19.65)

0.3501

0.03368

 1

2645(33.81)

2603(33.28)

 2

1649(21.08)

1642(20.99)

 3

877(11.21)

855(10.93)

  ≥ 4

1215(15.53)

1185(15.15)

History of comorbidities in previous year

 Hypertension

2741(35.04)

2671(34.15)

0.2394

0.01881

 Diabetes

1558(19.92)

1519(19.42)

0.4328

0.01254

 Hyperlipidaemia

1319(16.86)

1313(16.79)

0.898

0.00205

 Ischaemic heart disease

633(8.09)

595(7.61)

0.2586

0.01806

 Sleep disorder

600(7.67)

559(7.15)

0.2107

0.02001

 Alcohol-related illness

238(3.04)

225(2.88)

0.5397

0.00981

 Epilepsy

67(0.86)

62(0.79)

0.6585

0.00707

 Cancer

895(11.44)

874(11.17)

0.596

0.00848

 Arthritis

1552(19.84)

1537(19.65)

0.7632

0.00482

 Parkinson’s disease

41(0.52)

42(0.54)

0.9124

0.00176

 Dementia

72(0.92)

86(1.1)

0.2629

0.0179

 Obesity

3(0.04)

7(0.09)

0.2058

0.02023

 Cerebrovascular disease

621(7.94)

606(7.75)

0.6555

0.00713

 Atherosclerosis

168(2.15)

160(2.05)

0.6553

0.00714

History of exacerbation in previous year

 0

62(0.79)

70(0.89)

0.4844

0.01118

 1

1636(20.92)

1688(21.58)

0.3095

0.01625

  ≥ 2

6124(78.29)

6064(77.52)

0.2476

0.01849

Healthcare utilization in previous year

 Hospitalization

1327(16.96)

1347(17.22)

0.671

0.00679

 ED visit

723(9.24)

701(8.96)

0.5409

0.00978

 Outpatient visit

7321(93.59)

7302(93.35)

0.5385

0.00983

Insurance type

 Health insurance

7529(96.25)

7504(95.93)

0.3022

0.0165

 Medical-aid beneficiary

293(3.75)

318(4.07)

Index year

 2003

1483(18.96)

1435(18.35)

0.3245

0.01575

 2004

1107(14.15)

1032(13.19)

0.0809

0.02791

 2005

910(11.63)

943(12.06)

0.4142

0.01306

 2006

847(10.83)

916(11.71)

0.0811

0.0279

 2007

765(9.78)

816(10.43)

0.1761

0.02163

 2008

770(9.84)

809(10.34)

0.3006

0.01655

 2009

768(9.82)

714(9.13)

0.1404

0.02358

 2010

565(7.22)

547(6.99)

0.5754

0.00896

 2011

607(7.76)

610(7.8)

0.9286

0.00143

  1. ACO asthma-COPD overlap, COPD chronic obstructive pulmonary disease, ED emergency department
  2. aA standardized mean difference of greater than 0.1 represents significant difference between the two cohorts