TY - JOUR AU - Vestbo, J. AU - Hurd, S. S. AU - Agustí, A. G. AU - Jones, P. W. AU - Vogelmeier, C. AU - Anzueto, A. PY - 2013 DA - 2013// TI - Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease: GOLD executive summary JO - Am J Respir Crit Care Med VL - 187 UR - https://doi.org/10.1164/rccm.201204-0596PP DO - 10.1164/rccm.201204-0596PP ID - Vestbo2013 ER - TY - JOUR AU - Hersh, C. P. AU - Hokanson, J. E. AU - Lynch, D. A. AU - Washko, G. R. AU - Make, B. J. AU - Crapo, J. D. PY - 2011 DA - 2011// TI - Family history is a risk factor for COPD JO - Chest. VL - 140 UR - https://doi.org/10.1378/chest.10-2761 DO - 10.1378/chest.10-2761 ID - Hersh2011 ER - TY - JOUR AU - McCloskey, S. AU - Patel, B. AU - Hinchliffe, S. AU - Reid, E. AU - Wareham, N. AU - Lomas, D. PY - 2001 DA - 2001// TI - Siblings of patients with severe chronic obstructive pulmonary disease have a significant risk of airflow obstruction JO - Am J Respir Crit Care Med VL - 164 UR - https://doi.org/10.1164/ajrccm.164.8.2105002 DO - 10.1164/ajrccm.164.8.2105002 ID - McCloskey2001 ER - TY - STD TI - Silverman EK. Genetics of Chronic Obstructive Pulmonary Disease. In: Chadwick D, Goode JA, editors. Chronic Obstructive Pulmonary Disease: Pathogenesis to Treatment. New Jersey: Wiley; 2000. p. 45–64. ID - ref4 ER - TY - JOUR AU - Silverman, E. K. AU - Chapman, H. A. AU - Drazen, J. M. AU - Weiss, S. T. AU - Rosner, B. AU - Campbell, E. J. PY - 1998 DA - 1998// TI - Genetic epidemiology of severe, early-onset chronic obstructive pulmonary disease. Risk to relatives for airflow obstruction and chronic bronchitis JO - Am J Respir Crit Care Med VL - 157 UR - https://doi.org/10.1164/ajrccm.157.6.9706014 DO - 10.1164/ajrccm.157.6.9706014 ID - Silverman1998 ER - TY - JOUR AU - Cho, M. H. AU - Boutaoui, N. AU - Klanderman, B. J. AU - Sylvia, J. S. AU - Ziniti, J. P. AU - Hersh, C. P. PY - 2010 DA - 2010// TI - Variants in FAM13A are associated with chronic obstructive pulmonary disease JO - Nat Genet VL - 42 UR - https://doi.org/10.1038/ng.535 DO - 10.1038/ng.535 ID - Cho2010 ER - TY - JOUR AU - Cho, M. H. AU - Castaldi, P. J. AU - Wan, E. S. AU - Siedlinski, M. AU - Hersh, C. P. AU - Demeo, D. L. PY - 2012 DA - 2012// TI - A genome-wide association study of COPD identifies a susceptibility locus on chromosome 19q13 JO - Hum Mol Genet VL - 21 UR - https://doi.org/10.1093/hmg/ddr524 DO - 10.1093/hmg/ddr524 ID - Cho2012 ER - TY - JOUR AU - Cho, M. H. AU - McDonald, M. -. L. N. AU - Zhou, X. AU - Mattheisen, M. AU - Castaldi, P. J. AU - Hersh, C. P. PY - 2014 DA - 2014// TI - Risk loci for chronic obstructive pulmonary disease: a genome-wide association study and meta-analysis JO - Lancet Respir Med VL - 2 UR - https://doi.org/10.1016/S2213-2600(14)70002-5 DO - 10.1016/S2213-2600(14)70002-5 ID - Cho2014 ER - TY - JOUR AU - Cho, M. H. AU - Castaldi, P. J. AU - Hersh, C. P. AU - Hobbs, B. D. AU - Barr, R. G. AU - Tal-Singer, R. PY - 2015 DA - 2015// TI - A genome-wide association study of emphysema and airway quantitative imaging phenotypes JO - Am J Respir Crit Care Med VL - 192 UR - https://doi.org/10.1164/rccm.201501-0148OC DO - 10.1164/rccm.201501-0148OC ID - Cho2015 ER - TY - JOUR AU - Hobbs, B. D. AU - Jong, K. AU - Lamontagne, M. AU - Bossé, Y. AU - Shrine, N. AU - Artigas, M. S. PY - 2017 DA - 2017// TI - Genetic loci associated with chronic obstructive pulmonary disease overlap with loci for lung function and pulmonary fibrosis JO - Nat Genet VL - 49 UR - https://doi.org/10.1038/ng.3752 DO - 10.1038/ng.3752 ID - Hobbs2017 ER - TY - JOUR AU - Sakornsakolpat, P. AU - Prokopenko, D. AU - Lamontagne, M. AU - Reeve, N. F. AU - Guyatt, A. L. AU - Jackson, V. E. PY - 2019 DA - 2019// TI - Genetic landscape of chronic obstructive pulmonary disease identifies heterogeneous cell-type and phenotype associations JO - Nat Genet VL - 51 UR - https://doi.org/10.1038/s41588-018-0342-2 DO - 10.1038/s41588-018-0342-2 ID - Sakornsakolpat2019 ER - TY - JOUR AU - Wain, L. V. AU - Shrine, N. AU - Artigas, M. S. AU - Erzurumluoglu, A. M. AU - Noyvert, B. AU - Bossini-Castillo, L. PY - 2017 DA - 2017// TI - Genome-wide association analyses for lung function and chronic obstructive pulmonary disease identify new loci and potential druggable targets JO - Nat Genet VL - 49 UR - https://doi.org/10.1038/ng.3787 DO - 10.1038/ng.3787 ID - Wain2017 ER - TY - JOUR AU - Castaldi, P. J. AU - Dy, J. AU - Ross, J. AU - Chang, Y. AU - Washko, G. R. AU - Curran-Everett, D. PY - 2014 DA - 2014// TI - Cluster analysis in the COPDGene study identifies subtypes of smokers with distinct patterns of airway disease and emphysema JO - Thorax. VL - 69 UR - https://doi.org/10.1136/thoraxjnl-2013-203601 DO - 10.1136/thoraxjnl-2013-203601 ID - Castaldi2014 ER - TY - JOUR AU - McDonough, J. E. AU - Yuan, R. AU - Suzuki, M. AU - Seyednejad, N. AU - Elliott, W. M. AU - Sanchez, P. G. PY - 2011 DA - 2011// TI - Small-airway obstruction and emphysema in chronic obstructive pulmonary disease JO - N Engl J Med VL - 365 UR - https://doi.org/10.1056/NEJMoa1106955 DO - 10.1056/NEJMoa1106955 ID - McDonough2011 ER - TY - JOUR AU - Hogg, J. C. AU - Chu, F. AU - Utokaparch, S. AU - Woods, R. AU - Elliott, W. M. AU - Buzatu, L. PY - 2004 DA - 2004// TI - The nature of small-airway obstruction in chronic obstructive pulmonary disease JO - N Engl J Med VL - 350 UR - https://doi.org/10.1056/NEJMoa032158 DO - 10.1056/NEJMoa032158 ID - Hogg2004 ER - TY - JOUR AU - Suzuki, M. AU - Sze, M. A. AU - Campbell, J. D. AU - Brothers, J. F. AU - Lenburg, M. E. AU - McDonough, J. E. PY - 2017 DA - 2017// TI - The cellular and molecular determinants of emphysematous destruction in COPD JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/s41598-017-10126-2 DO - 10.1038/s41598-017-10126-2 ID - Suzuki2017 ER - TY - JOUR AU - Chang, Y. AU - Glass, K. AU - Liu, Y. -. Y. AU - Silverman, E. K. AU - Crapo, J. D. AU - Tal-Singer, R. PY - 2016 DA - 2016// TI - COPD subtypes identified by network-based clustering of blood gene expression JO - Genomics. VL - 107 UR - https://doi.org/10.1016/j.ygeno.2016.01.004 DO - 10.1016/j.ygeno.2016.01.004 ID - Chang2016 ER - TY - JOUR AU - Bhattacharya, S. AU - Tyagi, S. AU - Srisuma, S. AU - Demeo, D. L. AU - Shapiro, S. D. AU - Bueno, R. PY - 2011 DA - 2011// TI - Peripheral blood gene expression profiles in COPD subjects JO - J Clin Bioinforma VL - 1 UR - https://doi.org/10.1186/2043-9113-1-12 DO - 10.1186/2043-9113-1-12 ID - Bhattacharya2011 ER - TY - JOUR AU - Morrow, J. D. AU - Qiu, W. AU - Chhabra, D. AU - Rennard, S. I. AU - Belloni, P. AU - Belousov, A. PY - 2015 DA - 2015// TI - Identifying a gene expression signature of frequent COPD exacerbations in peripheral blood using network methods JO - BMC Med Genet VL - 8 ID - Morrow2015 ER - TY - JOUR AU - Oudijk, E. -. J. D. PY - 2005 DA - 2005// TI - Systemic inflammation in COPD visualised by gene profiling in peripheral blood neutrophils JO - Thorax. VL - 60 UR - https://doi.org/10.1136/thx.2004.034009 DO - 10.1136/thx.2004.034009 ID - Oudijk2005 ER - TY - JOUR AU - Hobbs, B. D. AU - Hersh, C. P. PY - 2014 DA - 2014// TI - Integrative genomics of chronic obstructive pulmonary disease JO - Biochem Biophys Res Commun VL - 452 UR - https://doi.org/10.1016/j.bbrc.2014.07.086 DO - 10.1016/j.bbrc.2014.07.086 ID - Hobbs2014 ER - TY - JOUR AU - Spira, A. AU - Beane, J. AU - Shah, V. AU - Liu, G. AU - Schembri, F. AU - Yang, X. PY - 2004 DA - 2004// TI - Effects of cigarette smoke on the human airway epithelial cell transcriptome JO - Proc Natl Acad Sci VL - 101 UR - https://doi.org/10.1073/pnas.0401422101 DO - 10.1073/pnas.0401422101 ID - Spira2004 ER - TY - STD TI - Tilley AE, O’Connor TP, Hackett NR, Strulovici-Barel Y, Salit J, Amoroso N, et al. Biologic Phenotyping of the Human Small Airway Epithelial Response to Cigarette Smoking. Königshoff M, editor. PLoS ONE. 2011;6(7):e22798. ID - ref23 ER - TY - JOUR AU - Steiling, K. AU - Lenburg, M. E. AU - Spira, A. PY - 2009 DA - 2009// TI - Airway gene expression in chronic obstructive pulmonary disease JO - Proc Am Thorac Soc VL - 6 UR - https://doi.org/10.1513/pats.200907-076DP DO - 10.1513/pats.200907-076DP ID - Steiling2009 ER - TY - JOUR AU - Steiling, K. AU - Berge, M. AU - Hijazi, K. AU - Florido, R. AU - Campbell, J. AU - Liu, G. PY - 2013 DA - 2013// TI - A dynamic bronchial airway gene expression signature of chronic obstructive pulmonary disease and lung function impairment JO - Am J Respir Crit Care Med VL - 187 UR - https://doi.org/10.1164/rccm.201208-1449OC DO - 10.1164/rccm.201208-1449OC ID - Steiling2013 ER - TY - JOUR AU - Yeo, J. AU - Morales, D. A. AU - Chen, T. AU - Crawford, E. L. AU - Zhang, X. AU - Blomquist, T. M. PY - 2018 DA - 2018// TI - RNAseq analysis of bronchial epithelial cells to identify COPD-associated genes and SNPs JO - BMC Pulm Med VL - 18 UR - https://doi.org/10.1186/s12890-018-0603-y DO - 10.1186/s12890-018-0603-y ID - Yeo2018 ER - TY - JOUR AU - Obeidat, M. AU - Nie, Y. AU - Chen, V. AU - Shannon, C. P. AU - Andiappan, A. K. AU - Lee, B. PY - 2017 DA - 2017// TI - Network-based analysis reveals novel gene signatures in peripheral blood of patients with chronic obstructive pulmonary disease JO - Respir Res VL - 18 UR - https://doi.org/10.1186/s12931-017-0558-1 DO - 10.1186/s12931-017-0558-1 ID - Obeidat2017 ER - TY - STD TI - Reinhold D, Morrow JD, Jacobson S, Hu J, Ringel B, Seibold MA, et al. Meta-analysis of peripheral blood gene expression modules for COPD phenotypes. Chotirmall SH, editor. PLOS ONE. 2017;12(10):e0185682. ID - ref28 ER - TY - JOUR AU - Beineke, P. AU - Fitch, K. AU - Tao, H. AU - Elashoff, M. R. AU - Rosenberg, S. AU - Kraus, W. E. PY - 2012 DA - 2012// TI - A whole blood gene expression-based signature for smoking status JO - BMC Med Genet VL - 5 ID - Beineke2012 ER - TY - JOUR AU - Huan, T. AU - Joehanes, R. AU - Schurmann, C. AU - Schramm, K. AU - Pilling, L. C. AU - Peters, M. J. PY - 2016 DA - 2016// TI - A whole-blood transcriptome meta-analysis identifies gene expression signatures of cigarette smoking JO - Hum Mol Genet VL - 25 ID - Huan2016 ER - TY - JOUR AU - Parker, M. M. AU - Chase, R. P. AU - Lamb, A. AU - Reyes, A. AU - Saferali, A. AU - Yun, J. H. PY - 2017 DA - 2017// TI - RNA sequencing identifies novel non-coding RNA and exon-specific effects associated with cigarette smoking JO - BMC Med Genet VL - 10 ID - Parker2017 ER - TY - JOUR AU - Hiemstra, P. S. AU - McCray, P. B. AU - Bals, R. PY - 2015 DA - 2015// TI - The innate immune function of airway epithelial cells in inflammatory lung disease JO - Eur Respir J VL - 45 UR - https://doi.org/10.1183/09031936.00141514 DO - 10.1183/09031936.00141514 ID - Hiemstra2015 ER - TY - JOUR AU - Xue, J. AU - Schmidt, S. V. AU - Sander, J. AU - Draffehn, A. AU - Krebs, W. AU - Quester, I. PY - 2014 DA - 2014// TI - Transcriptome-based network analysis reveals a Spectrum model of human macrophage activation JO - Immunity. VL - 40 UR - https://doi.org/10.1016/j.immuni.2014.01.006 DO - 10.1016/j.immuni.2014.01.006 ID - Xue2014 ER - TY - JOUR AU - Heguy, A. AU - O’Connor, T. P. AU - Luettich, K. AU - Worgall, S. AU - Cieciuch, A. AU - Harvey, B. -. G. PY - 2006 DA - 2006// TI - Gene expression profiling of human alveolar macrophages of phenotypically normal smokers and nonsmokers reveals a previously unrecognized subset of genes modulated by cigarette smoking JO - J Mol Med VL - 84 UR - https://doi.org/10.1007/s00109-005-0008-2 DO - 10.1007/s00109-005-0008-2 ID - Heguy2006 ER - TY - JOUR AU - Bhattacharya, S. AU - Srisuma, S. AU - DeMeo, D. L. AU - Shapiro, S. D. AU - Bueno, R. AU - Silverman, E. K. PY - 2009 DA - 2009// TI - Molecular biomarkers for quantitative and discrete COPD phenotypes JO - Am J Respir Cell Mol Biol VL - 40 UR - https://doi.org/10.1165/rcmb.2008-0114OC DO - 10.1165/rcmb.2008-0114OC ID - Bhattacharya2009 ER - TY - JOUR AU - Campbell, J. D. AU - McDonough, J. E. AU - Zeskind, J. E. AU - Hackett, T. L. AU - Pechkovsky, D. V. AU - Brandsma, C. -. A. PY - 2012 DA - 2012// TI - A gene expression signature of emphysema-related lung destruction and its reversal by the tripeptide GHK JO - Genome Med VL - 4 ID - Campbell2012 ER - TY - JOUR AU - Faner, R. AU - Cruz, T. AU - Casserras, T. AU - López-Giraldo, A. AU - Noell, G. AU - Coca, I. PY - 2016 DA - 2016// TI - Network analysis of lung transcriptomics reveals a distinct B cell signature in emphysema JO - Am J Respir Crit Care Med VL - 193 UR - https://doi.org/10.1164/rccm.201507-1311OC DO - 10.1164/rccm.201507-1311OC ID - Faner2016 ER - TY - JOUR AU - Morrow, J. D. AU - Zhou, X. AU - Lao, T. AU - Jiang, Z. AU - DeMeo, D. L. AU - Cho, M. H. PY - 2017 DA - 2017// TI - Functional interactors of three genome-wide association study genes are differentially expressed in severe chronic obstructive pulmonary disease lung tissue JO - Sci Rep VL - 7 UR - https://doi.org/10.1038/srep44232 DO - 10.1038/srep44232 ID - Morrow2017 ER - TY - JOUR AU - Spira, A. AU - Beane, J. AU - Pinto-Plata, V. AU - Kadar, A. AU - Liu, G. AU - Shah, V. PY - 2004 DA - 2004// TI - Gene expression profiling of human lung tissue from smokers with severe emphysema JO - Am J Respir Cell Mol Biol VL - 31 UR - https://doi.org/10.1165/rcmb.2004-0273OC DO - 10.1165/rcmb.2004-0273OC ID - Spira2004 ER - TY - JOUR AU - Kim, W. J. AU - Lim, J. H. AU - Lee, J. S. AU - Lee, S. -. D. AU - Kim, J. H. AU - Oh, Y. -. M. PY - 2015 DA - 2015// TI - Comprehensive analysis of transcriptome sequencing data in the lung tissues of COPD subjects JO - Int J Genomics VL - 2015 ID - Kim2015 ER - TY - JOUR AU - Jeong, I. AU - Lim, J. -. H. AU - Oh, D. K. AU - Kim, W. J. AU - Oh, Y. -. M. PY - 2018 DA - 2018// TI - Gene expression profile of human lung in a relatively early stage of COPD with emphysema JO - Int J Chron Obstruct Pulmon Dis VL - 13 UR - https://doi.org/10.2147/COPD.S166812 DO - 10.2147/COPD.S166812 ID - Jeong2018 ER - TY - JOUR AU - Imkamp, K. AU - Berg, M. AU - Vermeulen, C. J. AU - Heijink, I. H. AU - Guryev, V. AU - Kerstjens, H. A. M. PY - 2018 DA - 2018// TI - Nasal epithelium as a proxy for bronchial epithelium for smoking-induced gene expression and expression quantitative trait loci JO - J Allergy Clin Immunol VL - 142 UR - https://doi.org/10.1016/j.jaci.2018.01.047 DO - 10.1016/j.jaci.2018.01.047 ID - Imkamp2018 ER - TY - JOUR AU - Boudewijn, I. M. AU - Faiz, A. AU - Steiling, K. AU - Wiel, E. AU - Telenga, E. D. AU - Hoonhorst, S. J. M. PY - 2017 DA - 2017// TI - Nasal gene expression differentiates COPD from controls and overlaps bronchial gene expression JO - Respir Res VL - 18 UR - https://doi.org/10.1186/s12931-017-0696-5 DO - 10.1186/s12931-017-0696-5 ID - Boudewijn2017 ER - TY - JOUR AU - Obeidat, M. AU - Nie, Y. AU - Fishbane, N. AU - Li, X. AU - Bossé, Y. AU - Joubert, P. PY - 2017 DA - 2017// TI - Integrative genomics of emphysema-associated genes reveals potential disease biomarkers JO - Am J Respir Cell Mol Biol VL - 57 UR - https://doi.org/10.1165/rcmb.2016-0284OC DO - 10.1165/rcmb.2016-0284OC ID - Obeidat2017 ER - TY - JOUR AU - Poliska, S. AU - Csanky, E. AU - Szanto, A. AU - Szatmari, I. AU - Mesko, B. AU - Szeles, L. PY - 2011 DA - 2011// TI - Chronic obstructive pulmonary disease-specific gene expression signatures of alveolar macrophages as well as peripheral blood monocytes overlap and correlate with lung function JO - Respiration. VL - 81 UR - https://doi.org/10.1159/000324297 DO - 10.1159/000324297 ID - Poliska2011 ER - TY - JOUR AU - Mele, M. AU - Ferreira, P. G. AU - Reverter, F. AU - DeLuca, D. S. AU - Monlong, J. AU - Sammeth, M. PY - 2015 DA - 2015// TI - The human transcriptome across tissues and individuals JO - Science. VL - 348 UR - https://doi.org/10.1126/science.aaa0355 DO - 10.1126/science.aaa0355 ID - Mele2015 ER - TY - STD TI - Pierson E, the GTEx Consortium, Koller D, Battle A, Mostafavi S. Sharing and Specificity of Co-expression Networks across 35 Human Tissues. Rigoutsos I, editor. PLOS Comput Biol. 2015;11(5):e1004220. ID - ref47 ER - TY - JOUR AU - Saha, A. AU - Kim, Y. AU - Gewirtz, A. D. H. AU - Jo, B. AU - Gao, C. AU - McDowell, I. C. PY - 2017 DA - 2017// TI - Co-expression networks reveal the tissue-specific regulation of transcription and splicing JO - Genome Res VL - 27 UR - https://doi.org/10.1101/gr.216721.116 DO - 10.1101/gr.216721.116 ID - Saha2017 ER - TY - JOUR AU - Sonawane, A. R. AU - Platig, J. AU - Fagny, M. AU - Chen, C. -. Y. AU - Paulson, J. N. AU - Lopes-Ramos, C. M. PY - 2017 DA - 2017// TI - Understanding tissue-specific gene regulation JO - Cell Rep VL - 21 UR - https://doi.org/10.1016/j.celrep.2017.10.001 DO - 10.1016/j.celrep.2017.10.001 ID - Sonawane2017 ER - TY - JOUR AU - Halloran, J. W. AU - Zhu, D. AU - Qian, D. C. AU - Byun, J. AU - Gorlova, O. Y. AU - Amos, C. I. PY - 2015 DA - 2015// TI - Prediction of the gene expression in normal lung tissue by the gene expression in blood JO - BMC Med Genet VL - 8 ID - Halloran2015 ER - TY - JOUR AU - Morrow, J. D. AU - Cho, M. H. AU - Platig, J. AU - Zhou, X. AU - DeMeo, D. L. AU - Qiu, W. PY - 2018 DA - 2018// TI - Ensemble genomic analysis in human lung tissue identifies novel genes for chronic obstructive pulmonary disease JO - Hum Genomics VL - 12 UR - https://doi.org/10.1186/s40246-018-0132-z DO - 10.1186/s40246-018-0132-z ID - Morrow2018 ER - TY - JOUR AU - Civelek, M. AU - Lusis, A. J. PY - 2013 DA - 2013// TI - Systems genetics approaches to understand complex traits JO - Nat Rev Genet. VL - 15 UR - https://doi.org/10.1038/nrg3575 DO - 10.1038/nrg3575 ID - Civelek2013 ER - TY - JOUR AU - Regan, E. A. AU - Hokanson, J. E. AU - Murphy, J. R. AU - Make, B. AU - Lynch, D. A. AU - Beaty, T. H. PY - 2011 DA - 2011// TI - Genetic epidemiology of COPD (COPDGene) study design JO - COPD J Chronic Obstr Pulm Dis VL - 7 UR - https://doi.org/10.3109/15412550903499522 DO - 10.3109/15412550903499522 ID - Regan2011 ER - TY - JOUR AU - Diaz, A. A. AU - Valim, C. AU - Yamashiro, T. AU - Estépar, R. S. J. AU - Ross, J. C. AU - Matsuoka, S. PY - 2010 DA - 2010// TI - Airway count and emphysema assessed by chest CT imaging predicts clinical outcome in smokers JO - Chest. VL - 138 UR - https://doi.org/10.1378/chest.10-0542 DO - 10.1378/chest.10-0542 ID - Diaz2010 ER - TY - JOUR AU - Love, M. I. AU - Huber, W. AU - Anders, S. PY - 2014 DA - 2014// TI - Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2 JO - Genome Biol VL - 15 UR - https://doi.org/10.1186/s13059-014-0550-8 DO - 10.1186/s13059-014-0550-8 ID - Love2014 ER - TY - JOUR AU - Leek, J. T. AU - Storey, J. D. PY - 2007 DA - 2007// TI - Capturing heterogeneity in gene expression studies by surrogate variable analysis JO - PLoS Genet VL - 3 UR - https://doi.org/10.1371/journal.pgen.0030161 DO - 10.1371/journal.pgen.0030161 ID - Leek2007 ER - TY - JOUR AU - Morrow, J. D. AU - Cho, M. H. AU - Hersh, C. P. AU - Pinto-Plata, V. AU - Celli, B. AU - Marchetti, N. PY - 2016 DA - 2016// TI - DNA methylation profiling in human lung tissue identifies genes associated with COPD JO - Epigenetics. VL - 11 UR - https://doi.org/10.1080/15592294.2016.1226451 DO - 10.1080/15592294.2016.1226451 ID - Morrow2016 ER - TY - JOUR AU - Buro-Auriemma, L. J. AU - Salit, J. AU - Hackett, N. R. AU - Walters, M. S. AU - Strulovici-Barel, Y. AU - Staudt, M. R. PY - 2013 DA - 2013// TI - Cigarette smoking induces small airway epithelial epigenetic changes with corresponding modulation of gene expression JO - Hum Mol Genet VL - 22 UR - https://doi.org/10.1093/hmg/ddt326 DO - 10.1093/hmg/ddt326 ID - Buro-Auriemma2013 ER - TY - JOUR AU - Boyle, J. O. AU - Gumus, Z. H. AU - Kacker, A. AU - Choksi, V. L. AU - Bocker, J. M. AU - Zhou, X. K. PY - 2010 DA - 2010// TI - Effects of cigarette smoke on the human Oral mucosal transcriptome JO - Cancer Prev Res (Phila Pa) VL - 3 UR - https://doi.org/10.1158/1940-6207.CAPR-09-0192 DO - 10.1158/1940-6207.CAPR-09-0192 ID - Boyle2010 ER - TY - JOUR AU - Bosse, Y. AU - Postma, D. S. AU - Sin, D. D. AU - Lamontagne, M. AU - Couture, C. AU - Gaudreault, N. PY - 2012 DA - 2012// TI - Molecular signature of smoking in human lung tissues JO - Cancer Res VL - 72 UR - https://doi.org/10.1158/0008-5472.CAN-12-1160 DO - 10.1158/0008-5472.CAN-12-1160 ID - Bosse2012 ER - TY - JOUR AU - Fukumoto, J. AU - Soundararajan, R. AU - Leung, J. AU - Cox, R. AU - Mahendrasah, S. AU - Muthavarapu, N. PY - 2016 DA - 2016// TI - The role of club cell phenoconversion and migration in idiopathic pulmonary fibrosis JO - Aging. VL - 8 UR - https://doi.org/10.18632/aging.101115 DO - 10.18632/aging.101115 ID - Fukumoto2016 ER - TY - JOUR AU - Jong, K. AU - Vonk, J. M. AU - Imboden, M. AU - Lahousse, L. AU - Hofman, A. AU - Brusselle, G. G. PY - 2017 DA - 2017// TI - Genes and pathways underlying susceptibility to impaired lung function in the context of environmental tobacco smoke exposure JO - Respir Res VL - 18 UR - https://doi.org/10.1186/s12931-017-0625-7 DO - 10.1186/s12931-017-0625-7 ID - Jong2017 ER - TY - JOUR AU - Thorgeirsson, T. E. AU - Gudbjartsson, D. F. AU - Surakka, I. AU - Vink, J. M. AU - Amin, N. AU - Geller, F. PY - 2010 DA - 2010// TI - Sequence variants at CHRNB3–CHRNA6 and CYP2A6 affect smoking behavior JO - Nat Genet VL - 42 UR - https://doi.org/10.1038/ng.573 DO - 10.1038/ng.573 ID - Thorgeirsson2010 ER - TY - JOUR AU - Bu, X. -. L. AU - Cao, G. -. Q. AU - Shen, L. -. L. AU - Xiang, Y. AU - Jiao, S. -. S. AU - Liu, Y. -. H. PY - 2015 DA - 2015// TI - Serum amyloid-Beta levels are increased in patients with chronic obstructive pulmonary disease JO - Neurotox Res VL - 28 UR - https://doi.org/10.1007/s12640-015-9552-x DO - 10.1007/s12640-015-9552-x ID - Bu2015 ER - TY - JOUR AU - Jin, M. AU - Lee, E. C. AU - Ra, S. W. AU - Fishbane, N. AU - Tam, S. AU - Criner, G. J. PY - 2018 DA - 2018// TI - Relationship of absolute telomere length with quality of life, exacerbations, and mortality in COPD JO - Chest. VL - 154 UR - https://doi.org/10.1016/j.chest.2018.05.022 DO - 10.1016/j.chest.2018.05.022 ID - Jin2018 ER - TY - JOUR AU - Meiners, S. AU - Eickelberg, O. AU - Königshoff, M. PY - 2015 DA - 2015// TI - Hallmarks of the ageing lung JO - Eur Respir J VL - 45 UR - https://doi.org/10.1183/09031936.00186914 DO - 10.1183/09031936.00186914 ID - Meiners2015 ER - TY - JOUR AU - Thannickal, V. J. AU - Murthy, M. AU - Balch, W. E. AU - Chandel, N. S. AU - Meiners, S. AU - Eickelberg, O. PY - 2015 DA - 2015// TI - Blue journal conference. Aging and susceptibility to lung disease JO - Am J Respir Crit Care Med VL - 191 UR - https://doi.org/10.1164/rccm.201410-1876PP DO - 10.1164/rccm.201410-1876PP ID - Thannickal2015 ER - TY - JOUR AU - Tsuji, T. AU - Aoshiba, K. AU - Nagai, A. PY - 2006 DA - 2006// TI - Alveolar cell senescence in patients with pulmonary emphysema JO - Am J Respir Crit Care Med VL - 174 UR - https://doi.org/10.1164/rccm.200509-1374OC DO - 10.1164/rccm.200509-1374OC ID - Tsuji2006 ER - TY - JOUR AU - Lomas, D. A. AU - Silverman, E. K. AU - Edwards, L. D. AU - Miller, B. E. AU - Coxson, H. O. AU - Tal-Singer, R. PY - 2008 DA - 2008// TI - Evaluation of serum CC-16 as a biomarker for COPD in the ECLIPSE cohort JO - Thorax. VL - 63 UR - https://doi.org/10.1136/thx.2008.102574 DO - 10.1136/thx.2008.102574 ID - Lomas2008 ER - TY - JOUR AU - Zemans, R. L. AU - Jacobson, S. AU - Keene, J. AU - Kechris, K. AU - Miller, B. E. AU - Tal-Singer, R. PY - 2017 DA - 2017// TI - Multiple biomarkers predict disease severity, progression and mortality in COPD JO - Respir Res VL - 18 UR - https://doi.org/10.1186/s12931-017-0597-7 DO - 10.1186/s12931-017-0597-7 ID - Zemans2017 ER - TY - JOUR AU - Barnes, P. J. PY - 2016 DA - 2016// TI - Inflammatory mechanisms in patients with chronic obstructive pulmonary disease JO - J Allergy Clin Immunol VL - 138 UR - https://doi.org/10.1016/j.jaci.2016.05.011 DO - 10.1016/j.jaci.2016.05.011 ID - Barnes2016 ER - TY - JOUR AU - Yang, I. V. AU - Luna, L. G. AU - Cotter, J. AU - Talbert, J. AU - Leach, S. M. AU - Kidd, R. PY - 2012 DA - 2012// TI - The peripheral blood transcriptome identifies the presence and extent of disease in idiopathic pulmonary fibrosis JO - PLoS One VL - 7 UR - https://doi.org/10.1371/journal.pone.0037708 DO - 10.1371/journal.pone.0037708 ID - Yang2012 ER - TY - JOUR AU - Munthe-Fog, L. AU - Hummelshoj, T. AU - Honoré, C. AU - Moller, M. E. AU - Skjoedt, M. O. AU - Palsgaard, I. PY - 2012 DA - 2012// TI - Variation in FCN1 affects biosynthesis of ficolin-1 and is associated with outcome of systemic inflammation JO - Genes Immun VL - 13 UR - https://doi.org/10.1038/gene.2012.27 DO - 10.1038/gene.2012.27 ID - Munthe-Fog2012 ER - TY - JOUR AU - Bahr, T. M. AU - Hughes, G. J. AU - Armstrong, M. AU - Reisdorph, R. AU - Coldren, C. D. AU - Edwards, M. G. PY - 2013 DA - 2013// TI - Peripheral blood mononuclear cell gene expression in chronic obstructive pulmonary disease JO - Am J Respir Cell Mol Biol VL - 49 UR - https://doi.org/10.1165/rcmb.2012-0230OC DO - 10.1165/rcmb.2012-0230OC ID - Bahr2013 ER - TY - JOUR AU - Jones, P. A. PY - 2012 DA - 2012// TI - Functions of DNA methylation: islands, start sites, gene bodies and beyond JO - Nat Rev Genet VL - 13 UR - https://doi.org/10.1038/nrg3230 DO - 10.1038/nrg3230 ID - Jones2012 ER - TY - JOUR AU - Sharma, G. AU - Hanania, N. A. AU - Shim, Y. M. PY - 2009 DA - 2009// TI - The aging immune system and its relationship to the development of chronic obstructive pulmonary disease JO - Proc Am Thorac Soc VL - 6 UR - https://doi.org/10.1513/pats.200904-022RM DO - 10.1513/pats.200904-022RM ID - Sharma2009 ER - TY - JOUR AU - Sundahl, N. AU - Bridelance, J. AU - Libert, C. AU - Bosscher, K. AU - Beck, I. M. PY - 2015 DA - 2015// TI - Selective glucocorticoid receptor modulation: new directions with non-steroidal scaffolds JO - Pharmacol Ther VL - 152 UR - https://doi.org/10.1016/j.pharmthera.2015.05.001 DO - 10.1016/j.pharmthera.2015.05.001 ID - Sundahl2015 ER - TY - JOUR AU - Calverley, P. M. A. AU - Jones, P. W. PY - 2007 DA - 2007// TI - Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary disease JO - N Engl J Med VL - 356 UR - https://doi.org/10.1056/NEJMoa063070 DO - 10.1056/NEJMoa063070 ID - Calverley2007 ER - TY - JOUR AU - Bauer, M. AU - Fink, B. AU - Seyfarth, H. -. J. AU - Wirtz, H. AU - Frille, A. PY - 2017 DA - 2017// TI - Tobacco-smoking induced GPR15-expressing T cells in blood do not indicate pulmonary damage JO - BMC Pulm Med. VL - 17 UR - https://doi.org/10.1186/s12890-017-0509-0 DO - 10.1186/s12890-017-0509-0 ID - Bauer2017 ER - TY - JOUR AU - Bazzan, E. AU - Turato, G. AU - Tinè, M. AU - Radu, C. M. AU - Balestro, E. AU - Rigobello, C. PY - 2017 DA - 2017// TI - Dual polarization of human alveolar macrophages progressively increases with smoking and COPD severity JO - Respir Res VL - 18 UR - https://doi.org/10.1186/s12931-017-0522-0 DO - 10.1186/s12931-017-0522-0 ID - Bazzan2017 ER -