TY - STD TI - Lipiäinen T, Peltoniemi M, Sarkhel S, Yrjönen T, Vuorela H, Urtti A, et al. Formulation and Stability of Cytokine Therapeutics. J Pharm Sci [Internet]. Elsevier; 2015 [cited 2019 Mar 5];104:307–26. Available from: https://www.sciencedirect.com/science/article/pii/S0022354915302161 UR - https://www.sciencedirect.com/science/article/pii/S0022354915302161 ID - ref1 ER - TY - JOUR AU - Schroder, K. AU - Hertzog, P. J. AU - Ravasi, T. AU - Hume, D. A. PY - 2003 DA - 2003// TI - Interferon-γ: an overview of signals, mechanisms and functions JO - J Leukoc Biol VL - 75 UR - https://doi.org/10.1189/jlb.0603252 DO - 10.1189/jlb.0603252 ID - Schroder2003 ER - TY - STD TI - Miller CHT, Maher SG, Young HA. Clinical use of interferon-γ. Ann N Y Acad Sci Wiley/Blackwell (10.1111); 2009;1182:69–79. ID - ref3 ER - TY - JOUR AU - Lyseng-Williamson, K. A. PY - 2015 DA - 2015// TI - Interferon γ-1b in chronic granulomatous disease and severe malignant osteopetrosis: a guide to its use in the USA JO - Drugs Ther Perspect VL - 31 UR - https://doi.org/10.1007/s40267-015-0222-0 DO - 10.1007/s40267-015-0222-0 ID - Lyseng-Williamson2015 ER - TY - STD TI - Zaidi MR, Merlino G. The two faces of interferon-γ in cancer. Clin Cancer Res. 2011:6118–24. ID - ref5 ER - TY - STD TI - Greenlee-Wacker MC, Nauseef WM. IFN-γ targets macrophage-mediated immune responses toward Staphylococcus aureus. J Leukoc Biol Wiley-Blackwell; 2017;101:751–758. ID - ref6 ER - TY - JOUR AU - Smaldone, G. C. PY - 2018 DA - 2018// TI - Repurposing of gamma interferon via inhalation delivery JO - Adv Drug Deliv Rev VL - 133 UR - https://doi.org/10.1016/j.addr.2018.06.004 DO - 10.1016/j.addr.2018.06.004 ID - Smaldone2018 ER - TY - JOUR AU - Raghu, G. AU - Brown, K. K. AU - Williamson, Z. AU - Bradford, W. Z. AU - Starko, K. AU - Noble, P. W. AU - Schwartz, D. A. AU - King, T. E. PY - 2004 DA - 2004// TI - A placebo-controlled trial of interferon gamma-1b in patients with idiopathic pulmonary fibrosis JO - N Engl J Med VL - 350 UR - https://doi.org/10.1056/NEJMoa030511 DO - 10.1056/NEJMoa030511 ID - Raghu2004 ER - TY - STD TI - Patton JS. Mechanisms of macromolecule absorption by the lungs. Adv Drug Deliv Rev. 1996:3–36. ID - ref9 ER - TY - JOUR AU - Jaffe, H. A. AU - Buhl, R. AU - Mastrangeli, A. AU - Holroyd, K. J. AU - Saltini, C. AU - Czerski, D. PY - 1991 DA - 1991// TI - Organ specific cytokine therapy. Local activation of mononuclear phagocytes by delivery of an aerosol of recombinant interferon-gamma to the human lung JO - J Clin Invest American Society for Clinical Investigation VL - 88 UR - https://doi.org/10.1172/JCI115291 DO - 10.1172/JCI115291 ID - Jaffe1991 ER - TY - JOUR AU - Fusiak, T. AU - Smaldone, G. C. AU - Condos, R. PY - 2015 DA - 2015// TI - Pulmonary fibrosis treated with inhaled interferon-gamma (IFN-γ) JO - J Aerosol Med Pulm Drug Deliv. VL - 28 UR - https://doi.org/10.1089/jamp.2015.1221 DO - 10.1089/jamp.2015.1221 ID - Fusiak2015 ER - TY - JOUR AU - Moss, R. B. AU - Mayer-Hamblett, N. AU - Wagener, J. AU - Daines, C. AU - Hale, K. AU - Ahrens, R. PY - 2005 DA - 2005// TI - Randomized, double-blind, placebo-controlled, dose-escalating study of aerosolized interferon gamma-1b in patients with mild to moderate cystic fibrosis lung disease JO - Pediatr Pulmonol VL - 39 UR - https://doi.org/10.1002/ppul.20152 DO - 10.1002/ppul.20152 ID - Moss2005 ER - TY - STD TI - Condos R, Hull FP, Schluger NW, Rom WN, Smaldone GC. Regional deposition of aerosolized interferon-gamma in pulmonary tuberculosis. Chest. Elsevier; 2004;125:2146–2155. ID - ref13 ER - TY - STD TI - Millard J, Ugarte-, Gil C, Moore. Multidrug resistant tuberculosis BMJ 2015;350–882. ID - ref14 ER - TY - JOUR AU - Condos, R. AU - Rom, W. N. AU - Schluger, N. W. PY - 1997 DA - 1997// TI - Treatment of multidrug-resistant pulmonary tuberculosis with interferon-γ via aerosol JO - Lancet. VL - 349 UR - https://doi.org/10.1016/S0140-6736(96)12273-X DO - 10.1016/S0140-6736(96)12273-X ID - Condos1997 ER - TY - STD TI - Mortensen NP, Durham P, Hickey AJ. The role of particle physico-chemical properties in pulmonary drug delivery for tuberculosis therapy. J Microencapsul. 2014:785–95. ID - ref16 ER - TY - JOUR AU - Ari, A. AU - Arı, A. PY - 2014 DA - 2014// TI - Jet, ultrasonic, and mesh nebulizers: an evaluation of nebulizers for better clinical outcomes JO - Eurasian J Pulmonol Eurasian J Pulmonol VL - 16 UR - https://doi.org/10.5152/ejp.2014.00087 DO - 10.5152/ejp.2014.00087 ID - Ari2014 ER - TY - STD TI - Ibrahim M, Verma R, Garcia-Contreras L. Inhalation drug delivery devices: technology update. Med Devices Evid Res. 2015:131–9. ID - ref18 ER - TY - JOUR AU - Heyder, J. PY - 2004 DA - 2004// TI - Deposition of inhaled particles in the human respiratory tract and consequences for regional targeting in respiratory drug delivery JO - Proc Am Thorac Soc VL - 1 UR - https://doi.org/10.1513/pats.200409-046TA DO - 10.1513/pats.200409-046TA ID - Heyder2004 ER - TY - JOUR AU - MacLoughlin, R. AU - Telfer, C. AU - Clark, A. AU - Fink, J. PY - 2017 DA - 2017// TI - Aerosol: a novel vehicle for pharmacotherapy in neonates JO - Curr Pharm Des VL - 23 UR - https://doi.org/10.2174/1381612823666170918122136 DO - 10.2174/1381612823666170918122136 ID - MacLoughlin2017 ER - TY - STD TI - Daniel RM, Cowan DA. Biomolecular stability and life at high temperatures. Cell Mol Life Sci. 2000:250–64. ID - ref21 ER - TY - STD TI - de Kruijf W, Ehrhardt C. Inhalation delivery of complex drugs — the next steps. Curr Opin Pharmacol. 2017:52–7. ID - ref22 ER - TY - JOUR AU - O’Riordan, T. G. PY - 2002 DA - 2002// TI - Formulations and nebulizer performance JO - Respir Care VL - 47 ID - O’Riordan2002 ER - TY - JOUR AU - Grahmann, P. R. AU - Braun, R. K. PY - 2008 DA - 2008// TI - A new protocol for multiple inhalation of IFN-γ successfully treats MDR-TB: a case study JO - Int J Tuberc Lung Dis VL - 12 ID - Grahmann2008 ER - TY - STD TI - Diaz KT, Skaria S, Harris K, Solomita M, Lau S, Bauer K, et al. Delivery and safety of inhaled interferon-γ in idiopathic pulmonary fibrosis. J aerosol med Pulm drug Deliv. Mary Ann Liebert, Inc. 140 Huguenot street, 3rd floor New Rochelle, NY 10801 USA ; 2012;25:79–87. ID - ref25 ER - TY - JOUR AU - O’Mahony, A. M. AU - Nolan, L. AU - O’Driscoll, C. M. AU - Hibbitts, A. AU - Desgranges, S. AU - Cryan, S. A. PY - 2014 DA - 2014// TI - Early-stage development of novel Cyclodextrin-siRNA Nanocomplexes allows for successful Postnebulization transfection of bronchial epithelial cells JO - J Aerosol Med Pulm Drug Deliv VL - 27 UR - https://doi.org/10.1089/jamp.2013.1045 DO - 10.1089/jamp.2013.1045 ID - O’Mahony2014 ER - TY - STD TI - United States pharmacopeia and National Formulary (USP 29-NF 24). 601 aerosols, nasal sprays, metered-dose inhalers, and dry powder inhalers. ID - ref27 ER - TY - JOUR AU - Dugernier, J. AU - Hesse, M. AU - Vanbever, R. AU - Depoortere, V. AU - Roeseler, J. AU - Michotte, J. B. PY - 2017 DA - 2017// TI - SPECT-CT comparison of lung deposition using a system combining a vibrating-mesh nebulizer with a Valved holding chamber and a conventional jet nebulizer: a randomized cross-over study JO - Pharm Res VL - 34 UR - https://doi.org/10.1007/s11095-016-2061-7 DO - 10.1007/s11095-016-2061-7 ID - Dugernier2017 ER - TY - JOUR AU - Branconnier, M. P. AU - Hess, D. R. PY - 2005 DA - 2005// TI - Albuterol delivery during noninvasive ventilation JO - Respir Care VL - 50 ID - Branconnier2005 ER - TY - JOUR AU - Bennett, G. AU - Joyce, M. AU - Sweeney, L. AU - MacLoughlin, R. PY - 2018 DA - 2018// TI - In vitro determination of the Main effects in the Design of High-Flow Nasal Therapy Systems with respect to aerosol performance JO - Pulm Ther VL - 4 UR - https://doi.org/10.1007/s41030-018-0054-x DO - 10.1007/s41030-018-0054-x ID - Bennett2018 ER - TY - JOUR AU - Hart, N. AU - Polkey, M. I. AU - Clément, A. AU - Boulé, M. AU - Moxham, J. AU - Lofaso, F. PY - 2002 DA - 2002// TI - Changes in pulmonary mechanics with increasing disease severity in children and Young adults with cystic fibrosis. Am J Respir Crit care med. American thoracic JO - Society VL - 166 ID - Hart2002 ER - TY - JOUR AU - Liu, M. AU - Guo, S. AU - Hibbert, J. M. AU - Jain, V. AU - Singh, N. AU - Wilson, N. O. PY - 2011 DA - 2011// TI - CXCL10/IP-10 in infectious diseases pathogenesis and potential therapeutic implications JO - Cytokine Growth Factor Rev Pergamon VL - 22 ID - Liu2011 ER - TY - JOUR AU - Hickey, A. J. AU - Durham, P. G. AU - Dharmadhikari, A. AU - Nardell, E. A. PY - 2016 DA - 2016// TI - Inhaled drug treatment for tuberculosis: past progress and future prospects JO - J Control Release VL - 240 UR - https://doi.org/10.1016/j.jconrel.2015.11.018 DO - 10.1016/j.jconrel.2015.11.018 ID - Hickey2016 ER - TY - JOUR AU - MacLoughlin, R. AU - Power, P. AU - Wolny, M. AU - Duffy, C. PY - 2013 DA - 2013// TI - Evaluation of vibrating mesh nebulizer performance during nasal high flow therapy JO - J Aerosol Med Pulm Drug Deliv VL - 26 ID - MacLoughlin2013 ER - TY - JOUR AU - Martin, R. J. AU - Boguniewicz, M. AU - Henson, J. E. AU - Celniker, A. C. AU - Williams, M. AU - Giorno, R. C. PY - 1993 DA - 1993// TI - The effects of inhaled interferon gamma in Normal human airways JO - Am Lung Assoc VL - 148 ID - Martin1993 ER - TY - JOUR AU - Wan, G. -. H. AU - Fink, J. B. AU - Lin, H. -. L. AU - Chen, Y. -. H. AU - Liu, W. -. Q. AU - Liu, K. -. Y. PY - 2012 DA - 2012// TI - Influence of nebulizer type with different pediatric aerosol masks on drug deposition in a model of a spontaneously breathing small child JO - Respir Care VL - 57 UR - https://doi.org/10.4187/respcare.01652 DO - 10.4187/respcare.01652 ID - Wan2012 ER - TY - JOUR AU - Brightling, C. E. AU - Ammit, A. J. AU - Kaur, D. AU - Black, J. L. AU - Wardlaw, A. J. AU - Hughes, J. M. PY - 2005 DA - 2005// TI - The CXCL10/CXCR3 Axis mediates human lung mast cell migration to asthmatic airway smooth muscle. Am J Respir Crit care med. American thoracic JO - Society VL - 171 ID - Brightling2005 ER - TY - JOUR AU - Raju, B. AU - Hoshino, Y. AU - Kuwabara, K. AU - Belitskaya, I. AU - Prabhakar, S. AU - Canova, A. PY - 2004 DA - 2004// TI - Aerosolized gamma interferon (IFN-γ) induces expression of the genes encoding the IFN-γ-inducible 10-Kilodalton protein but not inducible nitric oxide synthase in the lung during tuberculosis JO - Infect Immun VL - 72 UR - https://doi.org/10.1128/IAI.72.3.1275-1283.2004 DO - 10.1128/IAI.72.3.1275-1283.2004 ID - Raju2004 ER -