|
Age
|
67.9 ± 8.3
|
68.4 ± 7.8
|
0.67
|
|
Male
|
74(96.1)
|
345(91.5)
|
0.24
|
|
Smoking status
| | |
0.72
|
|
Current smoker
|
27(35.1)
|
116(31.1)
| |
|
Ex-smoker
|
46(59.7)
|
231(61.9)
| |
|
Non-smoker
|
4(5.2)
|
26(7.0)
| |
|
Pack-years
|
43.7 ± 25.6
|
43.4 ± 24.9
|
0.93
|
|
BMI
|
23.1 ± 3.5
|
23.0 ± 3.3
|
0.47
|
|
SGRQ
|
34.0 ± 19.4
|
33.0 ± 18.6
|
0.65
|
|
CAT
|
15.9 ± 0.9
|
16.3 ± 0.4
|
0.90
|
|
mMRC
|
1.5 ± 0.9
|
1.6 ± 0.8
|
0.71
|
|
Post-BD FEV1, L
|
1.45 ± 0.44
|
1.48 ± 0.54
|
0.63
|
|
Post-BD FEV1, % predicted
|
54.0 ± 15.3
|
55.9 ± 19.9
|
0.44
|
|
Post-BD FEV1/FVC ratio
|
47.6 ± 11.0
|
47.9 ± 12.5
|
0.83
|
|
Bronchodilator Response
| | |
0.41
|
|
None
|
67(87)
|
307(81.2)
| |
|
BDR > 12% and 200 ml (FEV1)
|
7(9.1)
|
56(14.8)
| |
|
BDR > 15% and 400 ml (FEV1) (Spanish ACO)
|
3(3.9)
|
15 (4.0)
| |
|
DLco, % predicteda
|
70.2 ± 24.0
|
74.1 ± 23.8
|
0.24
|
|
Asthma
|
43 (56.6)
|
152 (41)
|
0.01
|
|
Exacerbation frequency, events/person-year
|
0.79 ± 2.35
|
0.53 ± 1.39
|
< 0.001
|
|
Serum eosinophils cells/μlb
|
177(84–325)
|
190(113–327)
|
0.23
|
|
Eosinophils > 300 cells/μl n (%)
|
14(25.5)
|
79(28.9)
|
0.6
|
|
GOLD group
| | |
0.39
|
|
A
|
32(42.7)
|
171(46.1)
| |
|
B
|
28(37.3)
|
134(36.1)
| |
|
C
|
8(10.7)
|
21(5.7)
| |
|
D
|
7(9.3)
|
45(12.1)
| |
