TY - STD TI - Global, regional, and national age-sex specific mortality for 264 causes of death, 1980-2016: a systematic analysis for the Global Burden of Disease Study 2016. Lancet 2017, 390:1151–1210. ID - ref1 ER - TY - JOUR AU - Ramirez, J. A. AU - Wiemken, T. L. AU - Peyrani, P. AU - Arnold, F. W. AU - Kelley, R. AU - Mattingly, W. A. AU - Nakamatsu, R. AU - Pena, S. AU - Guinn, B. E. AU - Furmanek, S. P. PY - 2017 DA - 2017// TI - Adults hospitalized with pneumonia in the United States: incidence, epidemiology, and mortality JO - Clin Infect Dis VL - 65 UR - https://doi.org/10.1093/cid/cix647 DO - 10.1093/cid/cix647 ID - Ramirez2017 ER - TY - STD TI - National Health and Family Planning Commission C: China Health and Family Planning Statistics Yearbook (2013). Available from: http://www.nhfpc.gov.cn/htmlfiles/zwgkzt/ptjnj/year2013/index2013.html. UR - http://www.nhfpc.gov.cn/htmlfiles/zwgkzt/ptjnj/year2013/index2013.html ID - ref3 ER - TY - JOUR AU - Jain, S. AU - Self, W. H. AU - Wunderink, R. G. AU - Fakhran, S. AU - Balk, R. AU - Bramley, A. M. AU - Reed, C. AU - Grijalva, C. G. AU - Anderson, E. J. AU - Courtney, D. M. PY - 2015 DA - 2015// TI - Community-acquired pneumonia requiring hospitalization among U.S. adults JO - N Engl J Med VL - 373 UR - https://doi.org/10.1056/NEJMoa1500245 DO - 10.1056/NEJMoa1500245 ID - Jain2015 ER - TY - STD TI - World Population Prospects: The 2017 Revision | Multimedia Library - United Nations Department of Economic and Social Affairs. Available online: https://www.un.org/development/desa/publications/world-population-prospects-the-2017-revision.html. UR - https://www.un.org/development/desa/publications/world-population-prospects-the-2017-revision.html ID - ref5 ER - TY - JOUR AU - Hannun, Y. A. AU - Obeid, L. M. PY - 2008 DA - 2008// TI - Principles of bioactive lipid signalling: lessons from sphingolipids JO - Nat Rev Mol Cell Biol VL - 9 UR - https://doi.org/10.1038/nrm2329 DO - 10.1038/nrm2329 ID - Hannun2008 ER - TY - JOUR AU - Serhan, C. N. AU - Chiang, N. AU - Dyke, T. E. PY - 2008 DA - 2008// TI - Resolving inflammation: dual anti-inflammatory and pro-resolution lipid mediators JO - Nat Rev Immunol VL - 8 UR - https://doi.org/10.1038/nri2294 DO - 10.1038/nri2294 ID - Serhan2008 ER - TY - JOUR AU - Serhan, C. N. PY - 2014 DA - 2014// TI - Pro-resolving lipid mediators are leads for resolution physiology JO - Nature VL - 510 UR - https://doi.org/10.1038/nature13479 DO - 10.1038/nature13479 ID - Serhan2014 ER - TY - JOUR AU - Duvall, M. G. AU - Bruggemann, T. R. AU - Levy, B. D. PY - 2017 DA - 2017// TI - Bronchoprotective mechanisms for specialized pro-resolving mediators in the resolution of lung inflammation JO - Mol Asp Med VL - 58 UR - https://doi.org/10.1016/j.mam.2017.04.003 DO - 10.1016/j.mam.2017.04.003 ID - Duvall2017 ER - TY - JOUR AU - Ning, P. AU - Zheng, Y. AU - Luo, Q. AU - Liu, X. AU - Kang, Y. AU - Zhang, Y. AU - Zhang, R. AU - Xu, Y. AU - Yang, D. AU - Xi, W. PY - 2018 DA - 2018// TI - Metabolic profiles in community-acquired pneumonia: developing assessment tools for disease severity JO - Crit Care VL - 22 UR - https://doi.org/10.1186/s13054-018-2049-2 DO - 10.1186/s13054-018-2049-2 ID - Ning2018 ER - TY - JOUR AU - Mandell, L. A. AU - Wunderink, R. G. AU - Anzueto, A. AU - Bartlett, J. G. AU - Campbell, G. D. AU - Dean, N. C. AU - Dowell, S. F. AU - File, T. M. AU - Musher, D. M. AU - Niederman, M. S. PY - 2007 DA - 2007// TI - Infectious Diseases Society of America/American Thoracic Society consensus guidelines on the management of community-acquired pneumonia in adults JO - Clin Infect Dis VL - 44 UR - https://doi.org/10.1086/511159 DO - 10.1086/511159 ID - Mandell2007 ER - TY - JOUR AU - Evans, C. R. AU - Karnovsky, A. AU - Kovach, M. A. AU - Standiford, T. J. AU - Burant, C. F. AU - Stringer, K. A. PY - 2014 DA - 2014// TI - Untargeted LC-MS metabolomics of Bronchoalveolar lavage fluid differentiates acute respiratory distress syndrome from health JO - J Proteome Res VL - 13 UR - https://doi.org/10.1021/pr4007624 DO - 10.1021/pr4007624 ID - Evans2014 ER - TY - JOUR AU - Chen, S. AU - Hoene, M. AU - Li, J. AU - Li, Y. AU - Zhao, X. AU - Haring, H. U. AU - Schleicher, E. D. AU - Weigert, C. AU - Xu, G. AU - Lehmann, R. PY - 2013 DA - 2013// TI - Simultaneous extraction of metabolome and lipidome with methyl tert-butyl ether from a single small tissue sample for ultra-high performance liquid chromatography/mass spectrometry JO - J Chromatogr A VL - 1298 UR - https://doi.org/10.1016/j.chroma.2013.05.019 DO - 10.1016/j.chroma.2013.05.019 ID - Chen2013 ER - TY - JOUR AU - Tang, H. AU - Wang, X. AU - Xu, L. AU - Ran, X. AU - Li, X. AU - Chen, L. AU - Zhao, X. AU - Deng, H. AU - Liu, X. PY - 2016 DA - 2016// TI - Establishment of local searching methods for orbitrap-based high throughput metabolomics analysis JO - Talanta VL - 156 UR - https://doi.org/10.1016/j.talanta.2016.04.051 DO - 10.1016/j.talanta.2016.04.051 ID - Tang2016 ER - TY - JOUR AU - Bijlsma, S. AU - Bobeldijk, I. AU - Verheij, E. R. AU - Ramaker, R. AU - Kochhar, S. AU - Macdonald, I. A. AU - Van, O. B. AU - Smilde, A. K. PY - 2006 DA - 2006// TI - Large-scale human metabolomics studies: a strategy for data (pre-) processing and validation JO - Anal Chem VL - 78 UR - https://doi.org/10.1021/ac051495j DO - 10.1021/ac051495j ID - Bijlsma2006 ER - TY - JOUR AU - Yang, J. AU - Zhao, X. AU - Lu, X. AU - Lin, X. AU - Xu, G. PY - 2015 DA - 2015// TI - A data preprocessing strategy for metabolomics to reduce the mask effect in data analysis JO - Front Mol Biosci VL - 2 UR - https://doi.org/10.3389/fmolb.2015.00004 DO - 10.3389/fmolb.2015.00004 ID - Yang2015 ER - TY - JOUR AU - Kirwan, J. A. AU - Broadhurst, D. I. AU - Davidson, R. L. AU - Viant, M. R. PY - 2014 DA - 2014// TI - Erratum to: Characterising and correcting batch variation in an automated direct infusion mass spectrometry (DIMS) metabolomics workflow JO - Anal Bioanal Chem VL - 406 UR - https://doi.org/10.1007/s00216-014-8047-6 DO - 10.1007/s00216-014-8047-6 ID - Kirwan2014 ER - TY - JOUR AU - Berg, R. A. AU - Hoefsloot, H. C. J. AU - Westerhuis, J. A. AU - Smilde, A. K. AU - Werf, M. J. PY - 2006 DA - 2006// TI - Centering, scaling, and transformations: improving the biological information content of metabolomics data JO - BMC Genomics VL - 7 UR - https://doi.org/10.1186/1471-2164-7-142 DO - 10.1186/1471-2164-7-142 ID - Berg2006 ER - TY - JOUR AU - Chong, J. AU - Soufan, O. AU - Li, C. AU - Caraus, I. AU - Li, S. AU - Bourque, G. AU - Wishart, D. S. AU - Xia, J. PY - 2018 DA - 2018// TI - MetaboAnalyst 4.0: towards more transparent and integrative metabolomics analysis JO - Nucleic Acids Res VL - 46 UR - https://doi.org/10.1093/nar/gky310 DO - 10.1093/nar/gky310 ID - Chong2018 ER - TY - JOUR AU - Steinhaus, H. PY - 1956 DA - 1956// TI - Sur la division des corp materiels en parties JO - Bull Acad Polon Sci VL - 1 ID - Steinhaus1956 ER - TY - JOUR AU - Ketchen, D. J. AU - Shook, C. L. PY - 1996 DA - 1996// TI - The application of cluster analysis in strategic management research: an analysis and critique JO - Strateg Manag J VL - 17 UR - https://doi.org/3.0.CO;2-G DO - 3.0.CO;2-G ID - Ketchen1996 ER - TY - JOUR AU - Charrad, M. AU - Ghazzali, N. AU - Boiteau, V. AU - Niknafs, A. AU - Charrad, M. M. PY - 2014 DA - 2014// TI - Package ‘nbclust JO - J Stat Softw VL - 61 UR - https://doi.org/10.18637/jss.v061.i06 DO - 10.18637/jss.v061.i06 ID - Charrad2014 ER - TY - JOUR AU - Davies, L. C. AU - Jenkins, S. J. AU - Allen, J. E. AU - Taylor, P. R. PY - 2013 DA - 2013// TI - Tissue-resident macrophages JO - Nat Immunol VL - 14 UR - https://doi.org/10.1038/ni.2705 DO - 10.1038/ni.2705 ID - Davies2013 ER - TY - JOUR AU - Tisoncik-Go, J. AU - Gasper, D. J. AU - Kyle, J. E. AU - Eisfeld, A. J. AU - Selinger, C. AU - Hatta, M. AU - Morrison, J. AU - Korth, M. J. AU - Zink, E. M. AU - Kim, Y. -. M. PY - 2016 DA - 2016// TI - Integrated omics analysis of pathogenic host responses during pandemic H1N1 influenza virus infection: the crucial role of lipid metabolism JO - Cell Host Microbe VL - 19 UR - https://doi.org/10.1016/j.chom.2016.01.002 DO - 10.1016/j.chom.2016.01.002 ID - Tisoncik-Go2016 ER - TY - JOUR AU - Dennis, E. A. AU - Norris, P. C. PY - 2015 DA - 2015// TI - Eicosanoid storm in infection and inflammation JO - Nat Rev Immunol VL - 15 UR - https://doi.org/10.1038/nri3859 DO - 10.1038/nri3859 ID - Dennis2015 ER - TY - JOUR AU - Lemos, H. P. AU - Grespan, R. AU - Vieira, S. M. AU - Cunha, T. M. AU - Verri, W. A. AU - Fernandes, K. S. S. AU - Souto, F. O. AU - McInnes, I. B. AU - Ferreira, S. H. AU - Liew, F. Y. AU - Cunha, F. Q. PY - 2009 DA - 2009// TI - Prostaglandin mediates IL-23/IL-17-induced neutrophil migration in inflammation by inhibiting IL-12 and IFNγ production JO - Proc Natl Acad Sci VL - 106 UR - https://doi.org/10.1073/pnas.0812782106 DO - 10.1073/pnas.0812782106 ID - Lemos2009 ER - TY - JOUR AU - Wright, H. L. AU - Moots, R. J. AU - Bucknall, R. C. AU - Edwards, S. W. PY - 2010 DA - 2010// TI - Neutrophil function in inflammation and inflammatory diseases JO - Rheumatology VL - 49 UR - https://doi.org/10.1093/rheumatology/keq045 DO - 10.1093/rheumatology/keq045 ID - Wright2010 ER - TY - JOUR AU - Gómez-Muñoz, A. AU - Kong, J. AU - Salh, B. AU - Steinbrecher, U. P. PY - 2003 DA - 2003// TI - Sphingosine-1-phosphate inhibits acid sphingomyelinase and blocks apoptosis in macrophages JO - FEBS Lett VL - 539 UR - https://doi.org/10.1016/S0014-5793(03)00197-2 DO - 10.1016/S0014-5793(03)00197-2 ID - Gómez-Muñoz2003 ER - TY - JOUR AU - Fritsche, K. L. PY - 2015 DA - 2015// TI - The science of fatty acids and inflammation JO - Adv Nutr (Bethesda, Md) VL - 6 UR - https://doi.org/10.3945/an.114.006940 DO - 10.3945/an.114.006940 ID - Fritsche2015 ER - TY - JOUR AU - Glass, C. K. AU - Olefsky, J. M. PY - 2012 DA - 2012// TI - Inflammation and lipid signaling in the etiology of insulin resistance JO - Cell Metab VL - 15 UR - https://doi.org/10.1016/j.cmet.2012.04.001 DO - 10.1016/j.cmet.2012.04.001 ID - Glass2012 ER - TY - JOUR AU - Robblee, M. M. AU - Kim, C. C. AU - Porter Abate, J. AU - Valdearcos, M. AU - Sandlund, K. L. AU - Shenoy, M. K. AU - Volmer, R. AU - Iwawaki, T. AU - Koliwad, S. K. PY - 2016 DA - 2016// TI - Saturated fatty acids engage an IRE1alpha-dependent pathway to activate the NLRP3 Inflammasome in myeloid cells JO - Cell Rep VL - 14 UR - https://doi.org/10.1016/j.celrep.2016.02.053 DO - 10.1016/j.celrep.2016.02.053 ID - Robblee2016 ER - TY - JOUR AU - Suganami, T. AU - Tanimoto-Koyama, K. AU - Nishida, J. AU - Itoh, M. AU - Yuan, X. AU - Mizuarai, S. AU - Kotani, H. AU - Yamaoka, S. AU - Miyake, K. AU - Aoe, S. PY - 2007 DA - 2007// TI - Role of the toll-like receptor 4/NF-kappaB pathway in saturated fatty acid-induced inflammatory changes in the interaction between adipocytes and macrophages JO - Arterioscler Thromb Vasc Biol VL - 27 UR - https://doi.org/10.1161/01.ATV.0000251608.09329.9a DO - 10.1161/01.ATV.0000251608.09329.9a ID - Suganami2007 ER - TY - JOUR AU - Yan, Y. AU - Jiang, W. AU - Spinetti, T. AU - Tardivel, A. AU - Castillo, R. AU - Bourquin, C. AU - Guarda, G. AU - Tian, Z. AU - Tschopp, J. AU - Zhou, R. PY - 2013 DA - 2013// TI - Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation JO - Immunity VL - 38 UR - https://doi.org/10.1016/j.immuni.2013.05.015 DO - 10.1016/j.immuni.2013.05.015 ID - Yan2013 ER - TY - JOUR AU - Yamada, H. AU - Yoshida, M. AU - Nakano, Y. AU - Suganami, T. AU - Satoh, N. AU - Mita, T. AU - Azuma, K. AU - Itoh, M. AU - Yamamoto, Y. AU - Kamei, Y. PY - 2008 DA - 2008// TI - In vivo and in vitro inhibition of monocyte adhesion to endothelial cells and endothelial adhesion molecules by eicosapentaenoic acid JO - Arterioscler Thromb Vasc Biol VL - 28 UR - https://doi.org/10.1161/ATVBAHA.108.171736 DO - 10.1161/ATVBAHA.108.171736 ID - Yamada2008 ER - TY - JOUR AU - Whittington, R. A. AU - Planel, E. AU - Terrando, N. PY - 2017 DA - 2017// TI - Impaired resolution of inflammation in Alzheimer's disease: a review JO - Front Immunol VL - 8 UR - https://doi.org/10.3389/fimmu.2017.01464 DO - 10.3389/fimmu.2017.01464 ID - Whittington2017 ER - TY - JOUR AU - Sun, X. AU - Song, L. AU - Feng, S. AU - Li, L. AU - Yu, H. AU - Wang, Q. AU - Wang, X. AU - Hou, Z. AU - Li, X. AU - Li, Y. PY - 2018 DA - 2018// TI - Fatty acid metabolism is associated with disease severity after H7N9 infection JO - EBioMedicine VL - 33 UR - https://doi.org/10.1016/j.ebiom.2018.06.019 DO - 10.1016/j.ebiom.2018.06.019 ID - Sun2018 ER - TY - JOUR AU - Schmidt, R. AU - Luboeinski, T. AU - Markart, P. AU - Ruppert, C. AU - Daum, C. AU - Grimminger, F. AU - Seeger, W. AU - Gunther, A. PY - 2004 DA - 2004// TI - Alveolar antioxidant status in patients with acute respiratory distress syndrome JO - Eur Respir J VL - 24 UR - https://doi.org/10.1183/09031936.04.00120703 DO - 10.1183/09031936.04.00120703 ID - Schmidt2004 ER - TY - JOUR AU - Gallin, J. I. AU - Kaye, D. AU - O'Leary, W. M. PY - 1969 DA - 1969// TI - Serum lipids in infection JO - N Engl J Med VL - 281 UR - https://doi.org/10.1056/NEJM196911132812001 DO - 10.1056/NEJM196911132812001 ID - Gallin1969 ER - TY - JOUR AU - Khovidhunkit, W. AU - Memon, R. A. AU - Feingold, K. R. AU - Grunfeld, C. PY - 2000 DA - 2000// TI - Infection and inflammation-induced Proatherogenic changes of lipoproteins JO - J Infect Dis VL - 181 UR - https://doi.org/10.1086/315611 DO - 10.1086/315611 ID - Khovidhunkit2000 ER - TY - JOUR AU - Kerttula, Y. AU - Weber, T. PY - 1988 DA - 1988// TI - Serum lipids in pneumonia of different aetiology JO - Ann Clin Res VL - 20 ID - Kerttula1988 ER - TY - JOUR AU - Tam, V. C. PY - 2013 DA - 2013// TI - Lipidomic profiling of bioactive lipids by mass spectrometry during microbial infections JO - Semin Immunol VL - 25 UR - https://doi.org/10.1016/j.smim.2013.08.006 DO - 10.1016/j.smim.2013.08.006 ID - Tam2013 ER - TY - JOUR AU - Feingold, K. R. AU - Staprans, I. AU - Memon, R. AU - Moser, A. AU - Shigenaga, J. AU - Doerrler, W. AU - Dinarello, C. AU - Grunfeld, C. PY - 1992 DA - 1992// TI - Endotoxin rapidly induces changes in lipid metabolism that produce hypertriglyceridemia: low doses stimulate hepatic triglyceride production while high doses inhibit clearance JO - J Lipid Res VL - 33 ID - Feingold1992 ER - TY - JOUR AU - Gordon, B. R. AU - Parker, T. S. AU - Levine, D. M. AU - Saal, S. D. AU - Wang, J. C. AU - Sloan, B. J. AU - Barie, P. S. AU - Rubin, A. L. PY - 1996 DA - 1996// TI - Low lipid concentrations in critical illness: implications for preventing and treating endotoxemia JO - Crit Care Med VL - 24 UR - https://doi.org/10.1097/00003246-199604000-00006 DO - 10.1097/00003246-199604000-00006 ID - Gordon1996 ER - TY - JOUR AU - Nassaji, M. AU - Ghorbani, R. PY - 2012 DA - 2012// TI - Plasma lipid levels in patients with acute bacterial infections JO - Turkish J Med Sci VL - 42 ID - Nassaji2012 ER - TY - STD TI - Kaysen G, Ye X, Raimann JG, Wang Y, Topping A, Usvyat LA, Stuard S, Canaud B, van der Sande FM, Kooman JP: Lipid levels are inversely associated with infectious and all-cause mortality: international MONDO study results. J Lipid Res 2018:jlr. P084277. ID - ref45 ER - TY - JOUR AU - Ryan, A. J. AU - McCoy, D. M. AU - McGowan, S. E. AU - Salome, R. G. AU - Mallampalli, R. K. PY - 2003 DA - 2003// TI - Alveolar sphingolipids generated in response to TNF-α modifies surfactant biophysical activity JO - J Appl Physiol VL - 94 UR - https://doi.org/10.1152/japplphysiol.00184.2002 DO - 10.1152/japplphysiol.00184.2002 ID - Ryan2003 ER - TY - JOUR AU - Maceyka, M. AU - Spiegel, S. PY - 2014 DA - 2014// TI - Sphingolipid metabolites in inflammatory disease JO - Nature VL - 510 UR - https://doi.org/10.1038/nature13475 DO - 10.1038/nature13475 ID - Maceyka2014 ER -