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Fig. 2 | Respiratory Research

Fig. 2

From: Impact of prior and concurrent medication on exacerbation risk with long-acting bronchodilators in chronic obstructive pulmonary disease: a post hoc analysis

Fig. 2

Forest plot of HR (95% CI) for a first moderate/severe exacerbation: UMEC/VI versus PBO (a), UMEC versus PBO (b), and VI versus PBO (c). Risk of a first moderate/severe exacerbation was assessed using a Cox proportional hazards model for all medication subgroups separately, with covariates for study, treatment, smoking status at screening and center group. CI, confidence interval; HR, hazard ratio; ICS, inhaled corticosteroid; ITT, intent-to-treat; PBO, placebo; UMEC, umeclidinium; VI, vilanterol

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