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Table 3 Cox regression in relation to mortality risk

From: Type IV collagen turnover is predictive of mortality in COPD: a comparison to fibrinogen in a prospective analysis of the ECLIPSE cohort

Parameter

Hazard ratio (95% CI)

P value

Age

1.14 (1.0654–1.2201)

0.0001

BMI

1.01 (0.9548–1.0752)

0.6640

BODE

1.17 (0.9828–1.3958)

0.0774

Current smoking

0.17 (0.0564–0.6132)

0.0057

6MWD

0.99 (0.99–1.00)

0.0205

mMRC dyspnea score

1.55 (1.11–2.17)

0.0106

Prior AECOPD

1.00 (0.74–1.37)

0.98

Prior hospitalizations due to AECOPD

1.52 (1.02–2.26)

0.0375

C4Ma3 per SD

1.65 (1.33–2.03)

< 0.0001

C4Ma3 per SD (adjusted for confounders)

1.57 (1.29–1.92)

< 0.0001

TUM per SD

1.307 (1.08–1.58)

0.0064

Fibrinogen per SD

1.58 (1.28–1.94)

< 0.0001

Fibrinogen per SD (adjusted for confounders)

1.62 (1.31–1.99)

< 0.0001

  1. Cox regression in relation to mortality risk. BMI body mass index, BODE BMI, airflow obstruction, dyspnea and exercise capacity index, 6MWD 6-min walk distance, mMRC modified Medical Research Council score, AECOPD acute exacerbations of chronic pulmonary disease. Confounders included age, current smoking status, 6MWD, mMRC score and prior hospitalizations due to AECOPD