Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: a meta-analysis of randomized controlled trials

Table 1 Characteristics of 8 RCTs and baseline characteristics of patients

Study	Study design	Group	N	Male (n)	GA (wk)	BW (g)	Antenatal steroid	Surfactant (n)	Caffeine (n)
Bottino 2018 [20]	Randomized controlled crossover trial	nHFOV	15	NA	< 32	< 1500	NA	15	15
Bottino 2018 [20]	Randomized controlled crossover trial	nCPAP	15	NA	< 32	< 1500	NA	15	15
Klotz 2017 [16]	Randomized controlled crossover trial	nHFOV	13	2	26.1 (2.2)*	814.2 (208.2)*	13	13	13
Klotz 2017 [16]	Randomized controlled crossover trial	nCPAP	13	9	27.2 (2.0)*	1083.5 (359.1)*	13	13	13
Lou 2017 [21]	Randomized controlled trial	nHFOV	34	24	32.5 (1.3)*	1790 (350)*	13	34	NA
Lou 2017 [21]	Randomized controlled trial	nCPAP	31	22	32.4 (1.4)*	1850 (410)*	12	21	NA
Lou 2018 [22]	Randomized controlled trial	nHFOV	33	18	33.5 (1.5)*	1790 (330)*	12	33	NA
Lou 2018 [22]	Randomized controlled trial	BPCPAP	32	17	34.2 (1.6)*	1840 (420)*	11	32	NA
Malakian 2018 [23]	Randomized controlled trial	nHFOV	63	28	31.08 (2.9)*	1485.5 (470)*	36	21	NA
Malakian 2018 [23]	Randomized controlled trial	nCPAP	61	25	31.07 (2.8)*	1505.5 (490)*	31	23	NA
Mukerji 2017 [24]	Randomized controlled trial	nHFOV	16	1	26.1 (1.3)*	831.9 (150.1)*	12	10	NA
Mukerji 2017 [24]	Randomized controlled trial	BPCPAP	23	2	26.5 (1.6)*	878.0 (198.3)*	20	14	NA
Zhu 2017 [25]	Randomized controlled trial	nHFOV	37	22	31.7 (1.7)*	1670 (353)*	13	37	NA
Zhu 2017 [25]	Randomized controlled trial	nCPAP	39	21	32.0 (1.9)*	1735 (327)*	15	39	NA
Zhu 2017 [26]	Randomized controlled trial	nHFOV	17	10	31.7 (1.7)*	1670 (353)*	6	17	NA
Zhu 2017 [26]	Randomized controlled trial	nCPAP	21	12	32.0 (1.9)*	1735 (327)*	8	21	NA

ISSN: 1465-993X