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Table 1 Characteristics of 8 RCTs and baseline characteristics of patients

From: Noninvasive high-frequency oscillatory ventilation as respiratory support in preterm infants: a meta-analysis of randomized controlled trials

Study

Study design

Group

N

Male (n)

GA (wk)

BW (g)

Antenatal steroid

Surfactant (n)

Caffeine (n)

Bottino 2018 [20]

Randomized controlled crossover trial

nHFOV

15

NA

< 32

< 1500

NA

15

15

nCPAP

15

NA

< 32

< 1500

NA

15

15

Klotz 2017 [16]

Randomized controlled crossover trial

nHFOV

13

2

26.1 (2.2)*

814.2 (208.2)*

13

13

13

nCPAP

13

9

27.2 (2.0)*

1083.5 (359.1)*

13

13

13

Lou 2017 [21]

Randomized controlled trial

nHFOV

34

24

32.5 (1.3)*

1790 (350)*

13

34

NA

nCPAP

31

22

32.4 (1.4)*

1850 (410)*

12

21

NA

Lou 2018 [22]

Randomized controlled trial

nHFOV

33

18

33.5 (1.5)*

1790 (330)*

12

33

NA

BPCPAP

32

17

34.2 (1.6)*

1840 (420)*

11

32

NA

Malakian 2018 [23]

Randomized controlled trial

nHFOV

63

28

31.08 (2.9)*

1485.5 (470)*

36

21

NA

nCPAP

61

25

31.07 (2.8)*

1505.5 (490)*

31

23

NA

Mukerji 2017 [24]

Randomized controlled trial

nHFOV

16

1

26.1 (1.3)*

831.9 (150.1)*

12

10

NA

BPCPAP

23

2

26.5 (1.6)*

878.0 (198.3)*

20

14

NA

Zhu 2017 [25]

Randomized controlled trial

nHFOV

37

22

31.7 (1.7)*

1670 (353)*

13

37

NA

nCPAP

39

21

32.0 (1.9)*

1735 (327)*

15

39

NA

Zhu 2017 [26]

Randomized controlled trial

nHFOV

17

10

31.7 (1.7)*

1670 (353)*

6

17

NA

nCPAP

21

12

32.0 (1.9)*

1735 (327)*

8

21

NA

  1. NA Not Applicated, BW: Birth weight, *means ±SD