| |
Unadjusted analysis
|
Adjusted for sex, age, weight, SMI, % body fat
|
|---|
|
Men
|
Women
|
|---|
|
r
|
p-value
|
r
|
p-value
|
Coefficient (95% CI)
|
p-value
|
R2
|
|---|
|
Grip strength, kg
|
|
FVC, %-predicted
|
0.17
|
0.16
|
− 0.13
|
0.41
|
0.050 (− 0.022 to 0.122)
|
0.17
|
0.65
|
|
DLCO, %-predicted
|
0.16
|
0.21
|
0.22
|
0.20
|
0.115 (0.026 to 0.204)
|
0.01
|
0.67
|
|
CPI
|
−0.29
|
0.03
|
− 0.31
|
0.08
|
− 0.140 (− 0.247 to − 0.034)
|
0.01
|
0.66
|
|
Dyspnea (UCSD SOBQ)
|
−0.08
|
0.58
|
−0.07
|
0.71
|
−0.066 (− 0.122 to − 0.010)
|
0.02
|
0.68
|
|
Gait speed, m/s
|
|
FVC, %-predicted
|
0.35
|
0.003
|
0.16
|
0.30
|
0.004 (0.001 to 0.007)
|
0.01
|
0.10
|
|
DLCO, %-predicted
|
0.25
|
0.049
|
0.06
|
0.71
|
0.004 (0.0005 to 0.008)
|
0.03
|
0.07
|
|
CPI
|
−0.29
|
0.02
|
−0.06
|
0.72
|
−0.006 (− 0.011 to − 0.002)
|
0.009
|
0.08
|
|
Dyspnea (UCSD SOBQ)
|
− 0.28
|
0.04
|
− 0.49
|
0.003
|
− 0.005 (− 0.007 to − 0.002)
|
0.0003
|
0.16
|
- Coefficients are reported per one-unit change for the predictor variables. A positive coefficient indicates an increase in the outcome variable per unit of the predictor variable (e.g., grip strength increases by an average of 0.115 kg for every 1% increase of DLCO %-predicted)
- Abbreviations: CI confidence interval, CPI composite physiologic index, DLCO diffusion capacity of the lung for carbon monoxide, FVC forced vital capacity, r Pearson’s correlation coefficient, R2 coefficient of determination (variability in the outcome explained by the model), SMI skeletal muscle index, UCSD SOBQ University of California San Diego Shortness of Breath Questionnaire
