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Fig. 7 | Respiratory Research

Fig. 7

From: Long non-coding RNA CASC2 suppresses pulmonary artery smooth muscle cell proliferation and phenotypic switch in hypoxia-induced pulmonary hypertension

Fig. 7

LncRNA CASC2 suppressed vascular remodeling of hypoxia-induced rat pulmonary arterial tissues. (a) Tissue fibrosis was measured by Masson′s trichrome staining in rat pulmonary arterial tissues and the collagen fiber was stained with blue. (b) The morphometric analysis of rat pulmonary arterial tissues was performed by hematoxylin and eosin (HE) staining. The parameters of pulmonary vascular cross-section were calculated by measuring the medial wall thickness, total vessel wall thickness, cross-sectional vessel area and wall area. (c) The percentage of medial wall thickness to the external diameter (WT%) was calculated in rats′ PAs tissues. (d) The percentage of cross-sectional total vessel wall area to the total area (WA %) was calculated in rat pulmonary arterial tissues. ### p < 0.001, compared with normoxia group. ** p < 0.01, compared with hypoxia + pcDNA3.1 group

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Respiratory Research

ISSN: 1465-993X

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