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Fig. 4 | Respiratory Research

Fig. 4

From: Long non-coding RNA CASC2 suppresses pulmonary artery smooth muscle cell proliferation and phenotypic switch in hypoxia-induced pulmonary hypertension

Fig. 4

LncRNA CASC2 was down-regulated in hypoxia-induced rats and reversed the increase of mPAP and progression of right ventricular hypertrophy caused by hypoxia. (a) The expression of lncRNA CASC2 was detected by qRT-PCR in rat pulmonary arterial tissues. (b) Systemic blood pressure (SBP) was assessed in normoxia and hypoxia-induced rats. (c) Mean pulmonary arterial pressure (mPAP) was detected in normoxia and hypoxia-induced rats. (d) The right ventricular hypertrophy index (RVI) was calculated in normoxia and hypoxia-induced rats. #p < 0.05, ##p < 0.01, ###p < 0.001, compared with normoxia group. **p < 0.01, compared with hypoxia + pcDNA3.1 group

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Respiratory Research

ISSN: 1465-993X

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