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Table 1 Levels of inflammatory cytokines and chemokines in the BAL fluid of mice from treatment groups

From: Ovalbumin-sensitized mice have altered airway inflammation to agriculture organic dust

Protein

Sal-Sal

Sal-ODE

OVA-Sal

OVA-ODE

TNF-α

31.6 ± 11.8

471.0 ± 68.9*

28.4 ± 11.5

223.7 ± 36.7*#

IL-6

21.8 ± 6.3

526.6 ± 91.7*

24.0 ± 9.1

1068 ± 120.2*#

IL-4

1.5 ± 0.8

0.8 ± 0.4

3.3 ± 1.0*

8.1 ± 3.2*#

IL-5

1.8 ± 0.6

2.8 ± 1.0

18.5 ± 7.8*#

7.1 ± 2.1

IL-13

0.1 ± 0.1

0.0 ± 0.0

14.6 ± 1.5*#

16.7 ± 2.4*#

CCL2

9.1 ± 0.4

36.1 ± 11.9*

14.5 ± 3.5

35.7 ± 17.2*

CCL3

15.0 ± 10.0

5493 ± 1065*%

766.1 ± 339.7*

4878 ± 1427 *%

CCL11

3.8 ± 0.5

7.0 ± 1.7

21.1 ± 5.9*

14.2 ± 2.6

CCL12

7.5 ± 0.3

10.0 ± 0.6

129.8 ± 55.3*

231.2 ± 50.7*#

CCL22

13.5 ± 2.4

89.7 ± 35.7

295.0 ± 118.8*

851.9 ± 272.3*#

CXCL1

71.5 ± 19.2

1336 ± 320.1* %

144.7 ± 28.7

1037 ± 307.0*

CXCL2

33.5 ± 13.3

287.9 ± 60.3*%

27.2 ± 14.51

197.0 ± 37.5*%

  1. Values (pg/ml) are mean ± standard error of mean. N = 4–8 mice/group
  2. Statistical significance versus Sal-Sal denoted as *(p < 0.05); versus Sal-ODE denoted as #(p < 0.05) and bolded; versus OVA-Sal %(p < 0.05). IL-9, IL-17A, IL-17E, IL-33 and CCL8 were not detected