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Fig. 9 | Respiratory Research

Fig. 9

From: Role of RASEF hypermethylation in cigarette smoke-induced pulmonary arterial smooth muscle remodeling

Fig. 9

Influence of Ad.RASEF on CSE-induced HPASMCs proliferation and migration changes. a Ad.RASEF transfection increased RASEF protein levels in HPASMCs. Transfection of HPASMCs with Ad.RASEF inhibited CSE-induced increases in cell proliferation [EdU positivity] (b), reduced S and G2/M phase and increased G0/G1 phase populations (c, f), promoted apoptosis (d, g), and prevented HPASMCs migration (e, h). Scale bar = 100 μm. Data are displayed as the mean ± standard error of the mean (n = 3); *P < 0.05, **P < .001, ***P < 0.001

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Respiratory Research

ISSN: 1465-993X

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