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Fig. 3 | Respiratory Research

Fig. 3

From: Role of RASEF hypermethylation in cigarette smoke-induced pulmonary arterial smooth muscle remodeling

Fig. 3

Effect of 5-Aza on CSE-induced HPASMCs proliferation and apoptosis changes. HPASMCs pretreatment with various concentration of 5-Aza (0, 0.5, 1, 2, 5, and 10 μM) for 48 h decreased DNMT1 protein levels (a, b) but did not affect the number of apoptotic cells (c). d CCK8 assay revealed pretreatment with 5-Aza (2 μM) inhibited CSE-induced increases in HPASMCs viability. Data are displayed as the mean ± standard error of the mean (n = 3); *P < 0.05, **P < 0.01

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Respiratory Research

ISSN: 1465-993X

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