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Table 1 Baseline patient characteristics

From: Prognostic impact of residual SYNTAX score in patients with obstructive sleep apnea and acute coronary syndrome: a prospective cohort study

 

OSA (N = 373)

non-OSA (N = 379)

P value

Age, years (mean ± SD)

57.6 ± 10.4

56.8 ± 10.0

0.299

Male, n (%)

315, 84.5%

306, 80.7%

0.211

BMI

27.6 ± 3.4

25.8 ± 3.3

< 0.001

AHI

33.7 ± 15.1

7.1 ± 4.0

< 0.001

bSS

14.9 ± 11.0

14.4 ± 11.8

0.350

rSS

7.8 ± 8.3

7.4 ± 9.1

0.054

Hypertension requiring medication, n (%)

255, 68.4%

239, 63.1%

0.144

Hyper cholesterolemia requiring medication, n (%)

103, 27.6%

98, 25.9%

0.621

Diabetes mellitus requiring medication, n (%)

112, 30%

118, 31.1%

0.752

Myocardial infarction history, n (%)

57, 15.3%

52, 13.7%

0.605

Cardiac Intervention history, n (%)

78, 20.9%

54, 14.2%

0.017

Time to last cardiac intervention, (days)

57 ± 49.6

67 ± 75

0.837

 Current smokers, n (%)

237, 63.5%

247, 65.2%

0.649

 Family history of CAD, n (%)

31, 8.3%

26, 6.9%

0.492

 Minimal SO2, %

86.4 ± 4.5

79.4 ± 8.6

< 0.001

 Mean SO2, %

93.0 ± 2.3

94.6 ± 1.7

< 0.001

 ODI

33.1 ± 16.1

7.9 ± 5.2

< 0.001

Clinical presentation

  

0.523

 STEMI, n (%)

124, 33.2%

119, 31.4%

 

 NSTEMI, n (%)

87, 23.3%

102, 26.9%

 

 Unstable Angina Pectoris, n (%)

162, 43.4%

158, 41.7%

 

LVEF,%

59.5 ± 7.7

59.8 ± 8.0

0.605

Post-procedural medication, n (%)

 ACE inhibitors or ARB

271, 72.7%

258, 68.1%

0.175

 Beta-blockers

290, 77.7%

284, 74.9%

0.391

Antiplatelet therapy

 Aspirin

354, 94.9%

354, 93.4%

0.438

 P2Y12 inhibitor

342, 91.7%

331, 87.3%

0.057

 Statin

357, 95.7%

356, 93.9%

0.324

Anatomical characteristics

 Multi-vessel disease, n (%)

  

0.024

  Three vessel disease, n (%)

102, 27.3%

86, 22.7%

 

  Two vessel disease, n (%)

143, 38.3%

122, 32.2%

 

Left main disease, n (%)

12, 3.2%

17, 4.5%

0.45

Any total occlusions

88, 23.6%

58, 15.3%

0.004

Any bifurcation

210, 61.4%

198, 58.8%

0.764

Any aorta-ostial lesion

 Diffuse disease

  Any lesion > 20 mm

90, 24.1%

78, 20.6%

0.256

  Any severe calcification

29, 7.8%

41, 10.8%

0.168

  Any severe tortuosity

32, 8.6%

22, 5.8%

0.159

  Any angiographically visible thrombus

53, 14.2%

63, 16.6%

0.366

Procedure related characteristics

 CABG, n (%)

34, 9.1%

41, 10.8%

0.467

 PCI, n (%)

58.7%

51.7%

0.057

 Total number of stent, n

1.0 ± 1.0

0.8 ± 1.0

0.046

 Hospital stay, n

4.9 ± 2.9

4.7 ± 2.9

0.371

  1. Values are shown in mean ± SD, or n (%)
  2. OSA obstructive sleep apnea; BMI = body mass index, AHI apnea hypopnea index, bSS baseline syntax score, rSS residual syntax score, CAD coronary artery disease, Mini SO2 minimal oxygen saturation, Mean SO2 mean oxygen saturation, ODI oxygen desaturation index, STEMI ST-segment elevation myocardial infarction, NSTEMI none ST-segment elevation myocardial infarction, LVEF left ventricular ejection fraction, ACE angiotensin converting enzyme, ARB angiotensin receptor blocker, CABG coronary artery bypass graft, PCI percutaneous coronary intervention