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Table 1 Patients characteristics at admission

From: Prognostic value of serum macrophage migration inhibitory factor levels in pulmonary tuberculosis

Characteristics

PTB

CAP

Control

N

287

100

100

Age (years), median (IQR)

57 (49–63)

57 (48–63)

57 (48–63)

Sex-male, n (%)

149 (51.9)

52 (52.0)

52 (52.0)

BMI (kg/m2), median (IQR)

24.3 (23.1–25.9)†‡

25.8 (24.3–27.4)

26.0 (24.8–28.5)

Current smoker, n (%)

63 (22.0)

24 (24.0)

21 (21.0)

Alcoholism, n (%)

13 (4.5)

4 (4.0)

3 (3.0)

Past history of tuberculosis, n (%)

19 (6.6)

Symptoms, n (%)

 Fever

133 (46.3)

100 (100.0)

 Cough or sputum

148 (51.6)

69 (69.0)

 Dyspnoea

55 (19.2)

59 (59.0)

 Chest pain

21 (7.3)

5 (5.0)

 Wight loss

53 (18.5)

3 (3.0)

Radiography findings

 Cavitary lesion

106 (36.9)

13 (13.0)

 Pleural effusion

54 (18.8)

14 (14.0)

PORT score

90.5 (80.7–105.6)

104.8 (92.5–116.3)

Positive sputum acid-fast smear, n (%)

165 (57.5)

Extent of disease, n (%)

 Minimal to mild disease

160 (55.7)

 Moderate

72 (25.1)

 Advanced disease

55 (19.2)

Drug resistant tuberculosisa, n (%)

38 (13.2)

Disseminated tuberculosis, n (%)

31 (10.8)

Death, n (%)

36 (12.5)

3 (3.0)

Laboratory test

 WBC 109/L

7.95 (7.10–9.33)†‡

12.1 (9.7–14.2)

5.88 (5.02–7.13)

 CRP, mg/dl

5.14 (4.03–6.55)†‡

10.15 (6.12–13.21)

0.23 (0.13–0.52)

 IL-6, ng/ml

10.8 (9.0–13.2)†‡

12.5 (9.8–16.6)

9.4 (6.9–11.9)

 MIF, ng/ml

23.0 (19.1–28.1)†‡

27.7 (21.7–33.5)

14.3 (10.9–17.2)

 FBG, mmol/l

5.79 (5.01–6.21)

5.66 (4.93–6.02)

5.38 (4.89–5.76)

 Albumin, g/dl

3.4 (3.2–3.7)

3.4 (3.1–3.7)

3.5 (3.2–3.7)

  1. Data are median (interquartile range) or n (%)
  2. †compared with CAP groups by chi-square or Mann–Whitney test and P < 0.05
  3. ‡compared with HC groups by chi-square or Mann–Whitney test and P < 0.05
  4. PTB Pulmonary Tuberculosis, CAP community-acquired pneumonia, BMI body mass index, WBC white blood cell count, CRP C-reactive protein, FBG fasting blood glucose, IL-6 Interleukin 6, MIF macrophage migration inhibitory factor