From: Prognostic value of serum macrophage migration inhibitory factor levels in pulmonary tuberculosis
Characteristics | PTB | CAP | Control |
---|---|---|---|
N | 287 | 100 | 100 |
Age (years), median (IQR) | 57 (49–63) | 57 (48–63) | 57 (48–63) |
Sex-male, n (%) | 149 (51.9) | 52 (52.0) | 52 (52.0) |
BMI (kg/m2), median (IQR) | 24.3 (23.1–25.9)†‡ | 25.8 (24.3–27.4) | 26.0 (24.8–28.5) |
Current smoker, n (%) | 63 (22.0) | 24 (24.0) | 21 (21.0) |
Alcoholism, n (%) | 13 (4.5) | 4 (4.0) | 3 (3.0) |
Past history of tuberculosis, n (%) | 19 (6.6) | – | – |
Symptoms, n (%) | |||
Fever | 133 (46.3)† | 100 (100.0) | – |
Cough or sputum | 148 (51.6)† | 69 (69.0) | – |
Dyspnoea | 55 (19.2)† | 59 (59.0) | – |
Chest pain | 21 (7.3) | 5 (5.0) | – |
Wight loss | 53 (18.5)† | 3 (3.0) | – |
Radiography findings | |||
Cavitary lesion | 106 (36.9)† | 13 (13.0) | – |
Pleural effusion | 54 (18.8) | 14 (14.0) | – |
PORT score | 90.5 (80.7–105.6)† | 104.8 (92.5–116.3) | – |
Positive sputum acid-fast smear, n (%) | 165 (57.5) | – | – |
Extent of disease, n (%) | |||
Minimal to mild disease | 160 (55.7) | – | – |
Moderate | 72 (25.1) | – | – |
Advanced disease | 55 (19.2) | – | – |
Drug resistant tuberculosisa, n (%) | 38 (13.2) | – | – |
Disseminated tuberculosis, n (%) | 31 (10.8) | – | – |
Death, n (%) | 36 (12.5) | 3 (3.0) | – |
Laboratory test | |||
WBC 109/L | 7.95 (7.10–9.33)†‡ | 12.1 (9.7–14.2) | 5.88 (5.02–7.13) |
CRP, mg/dl | 5.14 (4.03–6.55)†‡ | 10.15 (6.12–13.21) | 0.23 (0.13–0.52) |
IL-6, ng/ml | 10.8 (9.0–13.2)†‡ | 12.5 (9.8–16.6) | 9.4 (6.9–11.9) |
MIF, ng/ml | 23.0 (19.1–28.1)†‡ | 27.7 (21.7–33.5) | 14.3 (10.9–17.2) |
FBG, mmol/l | 5.79 (5.01–6.21) | 5.66 (4.93–6.02) | 5.38 (4.89–5.76) |
Albumin, g/dl | 3.4 (3.2–3.7) | 3.4 (3.1–3.7) | 3.5 (3.2–3.7) |