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Table 1 Organ weights in grams (mean ± standard deviation)

From: Pulmonary arterial remodelling by deficiency of peroxisome proliferator-activated receptor-γ in murine vascular smooth muscle cells occurs independently of obesity-related pulmonary hypertension

 

LFD

LFD

HFD

HFD

P

n

wild-type

SmPparγ−/−

wild-type

SmPparγ−/−

Liver

1.4 ± 0.4

1.6 ± 0.5

2.1 ± 0.9

2.3 ± 0.9

0.579 1

10–16

0.003 2

0.001 3

0.221 4

Kidney

0.5 ± 0.2

0.5 ± 0.2

0.6 ± 0.2

0.6 ± 0.2

0.575 1

10–16

0.009 2

< 0.001 3

0.529 4

AT perirenal

0.5 ± 0.7

0.9 ± 0.4

1.7 ± 1.1

1.7 ± 0.6

0.200 1

10–15

< 0.001 2

0.005 3

0.916 4

BAT

0.2 ± 0.1

0.3 ± 0.1

0.3 ± 0.1

0.3 ± 0.1

n.s.

9–11

AT epididymal

0.8 ± 0.3

1.3 ± 0.3

1.9 ± 0.2

1.7 ± 0.1

0.271 1

9–16

< 0.001 2

0.140 3

0.196 4

  1. Abbreviations: LFD low fat-diet, HFD high fat-diet, AT adipose tissue, BAT brown adipose tissue. n.s. non-significant; 1: LFD wild-type vs. LFD SmPparγ−/−; 2: LFD wild-type vs. HFD wild-type; 3: LFD SmPparγ−/− vs. HFD SmPparγ−/−; 4: HFD wild-type vs. HFD SmPparγ−/−
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Respiratory Research

ISSN: 1465-993X

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