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Table 2 Within- and between-group comparisons of the changes from baseline to endpoint measures for BMI, physical activity and some dietary intakes in the saffron and placebo groups of asthmatic patients

From: An evaluation of the effects of saffron supplementation on the asthma clinical symptoms and asthma severity in patients with mild and moderate persistent allergic asthma: a double-blind, randomized placebo-controlled trial

Variables

Saffron (N = 38)

Placebo(N = 38)

P-value*

Value

 

Value

P-value¥

BMI (kg/m2)

 Baseline

26.84 (25.46–27.23)

 

26.84 (25.05–27.39)

  

 8 weeks (endpoint)

26.68(25.81–27.18)

 

26.84 (24.79–27.44)

0.37

0.28

 Changes

0.00 (−0.35) to (0.00)

 

0.00 (0.00–0.32)

  

Physical activity (MET-min/week)

 Baseline

676.50 (231–2704)

 

693 (231–3446.50)

  

 8 weeks (endpoint)

660.00 (231.00–2220.50)

0.56

693.00 (379.50–3876.00)

0.02

0.28

 Changes

0.00 (0.00–90.75)

 

0.00 (0.00–173.250)

  

Energy intake (kilocalories)

 Baseline

1858.97 ± 213.16

 

1856.47 ± 99.66

  

 8 weeks (endpoint)

1865.36 ± 208.48

0.46

1877.44 ± 112.05

0.02

0.23

 Changes

32.00 (−41.00) to (46.25)

 

31.00 (−30.00) to (62.00)

  

Percent of calories from carbohydrate (%)

 Baseline

54.11 ± 6.63

 

57.15 ± 5.19

  

 8 weeks (endpoint)

54.65 ± 6.65

0.81

56.61 ± 6.36

0.16

0.20

 Changes

0.24 (−1.30) to (1.87)

 

0.21 (−2.21) to (0.77)

  

Percent of calories from protein (%)

 Baseline

11.69 ± 1.54

 

11.95 ± 1.51

  

 8 weeks (endpoint)

11.81 ± 1.46

 

11.81 ± 1.33

 

0.03

 Changes

0.13 (−0.24) to (0.47)

0.16

− 0.07 (− 0.47) to (0.12)

0.11

 

Percent of calories from fat (%)

 Baseline

33.80 ± 4.36

 

35.73 ± 6.03

  

 8 weeks (endpoint)

33.79 ± 4.35

 

36.47 ± 6.51

 

0.40

 Changes

0.23 (−1.97) to (2.02)

0.87

0.14 (−0.69) to (1.83)

0.21

 
  1. BMI Body Mass Index. *p-value for comparing the changes of variables between the groups. Mann-whitney test was used. ¥p-value for comparing baseline, with endpoint values within each group. Wilcoxon and Paired t test were used. Values are expressed as mean ± SD for parametric and median (25th, 75th percentiles) for non-parametric data