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Table 5 Associations between microRNA-144-3p expression and clinicopathological features in non-small cell lung cancer based on quantitative real-time PCR data

From: Down-regulation of microRNA-144-3p and its clinical value in non-small cell lung cancer: a comprehensive analysis based on microarray, miRNA-sequencing, and quantitative real-time PCR data

Clinicopathological feature   n mean ± SD p value
Tissue Adjacent non-cancerous tissue 125 4.813 ± 2.618 < 0.001*
NSCLC 125 2.808 ± 1.303
Age (years) < 60 57 2.7879 ± 1.33904 0.874
≥60 68 2.8254 ± 1.28196
Gender Female 50 2.9786 ± 1.40038 0.247
Male 75 2.6948 ± 1.23055
Tumor size (cm) ≤3 60 2.9242 ± 1.44526 0.346
> 3 65 2.7014 ± 1.15768
Smoke No 38 3.2489 ± 1.48252 0.166
Yes 30 2.7767 ± 1.29623
Lymph node metastasis No 56 3.0875 ± 1.38065 0.033*
Yes 69 2.5817 ± 1.19935
Vascular invasion No 90 3.0682 ± 1.24395 < 0.001*
Yes 35 2.1400 ± 1.22630
TNM I-II 54 2.9615 ± 1.27286 0.251
III-IV 71 2.6918 ± 1.32268
Histological type ADC 101 2.7917 ± 1.30837 0.561
SCC 23 2.9643 ± 1.26398
LCLC 1 0.9000  
  1. SD Standard deviation, NSCLC Non-small cell lung cancer, ADC Adenocarcinoma, SCC Squamous cell carcinoma, LCLC Large-cell lung carcinoma
  2. *p < 0.05 was considered statistically significant