Down-regulation of microRNA-144-3p and its clinical value in non-small cell lung cancer: a comprehensive analysis based on microarray, miRNA-sequencing, and quantitative real-time PCR data

Table 3 Association between microRNA-144-3p expression and clinicopathological parameters in lung adenocarcinoma, based on The Cancer Genome Atlas data

Clinicopathological		n	mean ± SD	p value
Tissue	Adjacent non-cancerous tissue	43	5.2775 ± 1.64708	< 0.001^*
Tissue	LUAD	445	2.8959 ± 1.35967	< 0.001^*
Age (years)	< 60	120	3.0042 ± 1.40207	0.168
Age (years)	≥60	306	2.7979 ± 1.33460	0.168
Gender	Female	239	2.9011 ± 1.33672	0.931
Gender	Male	206	2.8898 ± 1.38905	0.931
Tumor location	Central lung	54	2.5665 ± 1.1857	0.382
Tumor location	Peripheral lung	113	2.747 ± 1.3564	0.382
Stage	Stage I-II	349	2.8191 ± 1.33042	0.031^*
Stage	Stage III-IV	91	3.1868 ± 1.45395	0.031^*
T	T1-T2	385	2.9199 ± 1.35515	0.133
T	T3-T4	57	2.6359 ± 1.3106	0.133
N	No	291	2.8546 ± 1.35977	0.553
N	Yes	145	2.9367 ± 1.35784	0.553
M	No	283	2.8058 ± 1.31875	0.126
M	Yes	19	3.3343 ± 1.4003	0.126

ISSN: 1465-993X