Down-regulation of microRNA-144-3p and its clinical value in non-small cell lung cancer: a comprehensive analysis based on microarray, miRNA-sequencing, and quantitative real-time PCR data

Table 2 Association between microRNA-144-3p expression and clinicopathological parameters in lung squamous cell carcinoma, based on The Cancer Genome Atlas data

Clinicopathological feature		n	mean ± SD	p-value
Tissue	Adjacent non-cancerous tissue	44	5.5678 ± 1.27693	< 0.001^*
Tissue	LUSC	332	2.8193 ± 1.40600	< 0.001^*
Age (years)	< 60	59	2.7458 ± 1.32704	0.739
Age (years)	≥60	267	2.8106 ± 1.42109	0.739
Gender	Female	84	2.8195 ± 1.49697	0.999
Gender	Male	248	2.8192 ± 1.37698	0.999
Tumor location	Central lung	106	2.7551 ± 1.27303	0.848
Tumor location	Peripheral lung	73	2.7968 ± 1.51724	0.848
Stage	Stage I-II	276	2.8878 ± 1.39556	0.04^*
Stage	Stage III-IV	53	2.4469 ± 1.41079	0.04^*
T	T1-T2	262	2.9023 ± 1.40854	0.035^*
T	T3-T4	70	2.5088 ± 1.36178	0.035^*
N	No	213	2.8637 ± 1.43682	0.302
N	Yes	113	2.6987 ± 1.33482	0.302
M	No	252	2.7345 ± 1.38222	0.895
M	Yes	3	2.9144 ± 2.09106	0.895

ISSN: 1465-993X