Table 5 Test characteristics of rules with different prediction scores for mortality in the retrospective and prospective sets of patients hospitalized with CAP
From: Scored minor criteria for severe community-acquired pneumonia predicted better
Rule | No. Present or score | Sensitivity (%) | Specificity (%) | PPV (%) | NPV (%) | Youden’s index |
|---|---|---|---|---|---|---|
Retrospective cohort (n = 1230) | ||||||
IDSA/ATS minor criteria | ||||||
≥ 0 | 100 | 0 | 1.3 | 0 | 0 | |
≥ 1 | 87.5 | 53.7 | 2.4 | 99.7 | 0.41 | |
≥ 2 | 62.5 | 86.5 | 5.7 | 99.4 | 0.49 | |
≥ 3 | 37.5 | 96 | 11.1 | 99.1 | 0.34 | |
≥ 4 | 12.5 | 98.8 | 12.5 | 98.8 | 0.11 | |
≥ 5 | 12.5 | 99.8 | 50 | 98.9 | 0.12 | |
Scored minor criteria | ||||||
≥ 0 | 100 | 0 | 1.3 | 0 | 0 | |
≥ 1 | 87.5 | 53.7 | 2.4 | 99.7 | 0.41 | |
≥ 2 | 75 | 85.5 | 6.4 | 99.6 | 0.61 | |
≥ 3 | 62.5 | 93.2 | 10.9 | 99.5 | 0.56 | |
≥ 4 | 37.5 | 97 | 14 | 99.2 | 0.35 | |
≥ 5 | 25 | 98.5 | 18.2 | 99 | 0.24 | |
≥ 6 | 6.3 | 99.5 | 14.3 | 98.8 | 0.06 | |
≥ 7 | 6.3 | 99.8 | 33.3 | 98.8 | 0.06 | |
Prospective cohort (n = 1749) | ||||||
IDSA/ATS minor criteria | ||||||
≥ 0 | 100 | 0 | 4.5 | 0 | 0 | |
≥ 1 | 97.5 | 42.6 | 7.4 | 99.7 | 0.40 | |
≥ 2 | 89.9 | 64.9 | 10.8 | 99.3 | 0.55 | |
≥ 3 | 72.2 | 76.6 | 12.7 | 98.3 | 0.49 | |
≥ 4 | 36.7 | 90.5 | 15.5 | 96.8 | 0.27 | |
≥ 5 | 22.8 | 97.8 | 33.3 | 96.4 | 0.21 | |
Scored minor criteria | ||||||
≥ 0 | 100 | 0 | 4.5 | 0 | 0 | |
≥ 1 | 97.5 | 42.6 | 7.4 | 99.7 | 0.40 | |
≥ 2 | 92.4 | 63.6 | 10.7 | 99.4 | 0.56 | |
≥ 3 | 87.3 | 69.0 | 11.8 | 99.1 | 0.56 | |
≥ 4 | 78.5 | 75.4 | 13.1 | 98.7 | 0.54 | |
≥ 5 | 59.5 | 88.3 | 19.4 | 97.9 | 0.48 | |
≥ 6 | 35.4 | 95.6 | 27.7 | 96.9 | 0.31 | |
≥ 7 | 26.6 | 95.6 | 32.3 | 96.6 | 0.22 | |
≥ 8 | 22.8 | 97.8 | 33.3 | 96.4 | 0.21 | |