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Fig. 1 | Respiratory Research

Fig. 1

From: BAMBI regulates macrophages inducing the differentiation of Treg through the TGF-β pathway in chronic obstructive pulmonary disease

Fig. 1

M2 macrophages induce the differentiation of CD4 + CD25 + Foxp3+ T cells (Tregs) via the TGF-β/Smad signalling pathway. a. Percentage of Tregs in different groups (blank control, supernatant of M1 cells, M1 cells, supernatant of M2 cells and M2 cells). b. Concentration of TGF-β1 in monocyte-derived M2 macrophages before and after coculture. c. Western blot analysis of TGF-β/Smad signalling pathway in monocyte-derived M2 macrophages. d. The proportion of Tregs decreased compared with that in the untreated group after addition of LY2109761. *P < 0.05, ***P < 0.001

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