Association of plasma soluble CD14 level with asthma severity in adults: a case control study in China

Respiratory Research

Table 3 Association of plasma sCD14 level with asthma severity in adults

Asthma severity	Q1	Q2	Q3	Q4	LogCD14	P _trend
Asthma severity	< 398.54	398.54~607.51	607.51~855.01	> 855.01
Asthma/control	327/119	241/208	197/251	145/303
Adjusted OR (95% CI)	reference	0.45 (0.32, 0.62)	0.29 (0.21, 0.40)	0.19 (0.14, 0.26)	0.27 (0.22, 0.34)	< 0.0001
Intermittent/control	165/119	136/208	135/251	101/303
Adjusted OR (95% CI)	reference	0.48 (0.33, 0.68)	0.38 (0.27, 0.54)	0.25 (0.17, 0.35)	0.33 (0.26, 0.43)	< 0.0001
Mild/control	110/119	66/208	39/251	31/303
Adjusted OR (95% CI)	reference	0.38 (0.25, 0.58)	0.17 (0.11, 0.26)	0.12 (0.07, 0.20)	0.18 (0.14, 0.25)	< 0.0001
Moderate/control	37/119	28/208	19/251	12/303
Adjusted OR (95% CI)	reference	0.51 (0.28, 0.91)	0.25 (0.13, 0.47)	0.14 (0.07, 0.28)	0.21 (0.14, 0.32)	< 0.0001
Severe/control	15/119	11/208	4/251	1/303
Adjusted OR (95% CI)	reference	0.61 (0.25, 1.46)	0.14 (0.04, 0.45)	0.03 (0.003, 0.22)	0.15 (0.08, 0.28)	< 0.0001

Estimates were adjusted for age, sex, BMI, smoking status, passive smoking status, alcohol consumption, physical activity, family history of asthma, keeping pets, planting flowers, sleeping quality

ISSN: 1465-993X