Fig. 3

a) Global view of differentially expressed genes (DEG’s) b) Hierarchical clustering of samples based on DEGs with at least 2-fold change and controlled by false discovery rate of 0.1, as inferred from treated versus normal samples. Red indicates upregulation while blue indicates downregulation. In the sample clustering dendrogram, red indicates control samples, dark green indicates (LPS treated), blue indicates (fipronil at high dose 1/10th of LD₅₀), brown indicates (fipronil at high dose followed by LPS), light green indicates (fipronil at low 1/20th of LD₅₀ dose), while orange indicates (fipronil at low dose followed by LPS) samples. c) Venn diagram showing the overlap of DEG’s involved across LPS (CL), high dose of fipronil alone (F10) or in combination with LPS (FL10), low dose of fipronil alone (F20) or in combination with LPS (FL20) group